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Titolo:
EICOSANOIDS AND THE GASTROINTESTINAL-TRACT
Autore:
EBERHART CE; DUBOIS RN;
Indirizzi:
VANDERBILT UNIV,MED CTR,DEPT MED,GI,MCN C-2104 NASHVILLE TN 37232 VANDERBILT UNIV,MED CTR,DEPT MED,GI NASHVILLE TN 37232 VANDERBILT UNIV,MED CTR,DEPT CELL BIOL,GI NASHVILLE TN 37232 VET AFFAIRS MED CTR NASHVILLE TN 00000
Titolo Testata:
Gastroenterology
fascicolo: 1, volume: 109, anno: 1995,
pagine: 285 - 301
SICI:
0016-5085(1995)109:1<285:EATG>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFLAMMATORY BOWEL-DISEASE; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; GASTRIC-ACID SECRETION; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE; FAMILIAL ADENOMATOUS POLYPOSIS; INTESTINAL ELECTROLYTE TRANSPORT; MUCOSAL BLOOD-FLOW; RAT COLONIC EPITHELIUM; ULCERATIVE-COLITIS; CELL-PROLIFERATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
277
Recensione:
Indirizzi per estratti:
Citazione:
C.E. Eberhart e R.N. Dubois, "EICOSANOIDS AND THE GASTROINTESTINAL-TRACT", Gastroenterology, 109(1), 1995, pp. 285-301

Abstract

Determining the role of eicosanoids in gastrointestinal physiology and pathophysiology has been an active area of investigation over the past 20 years. The landmark discovery of prostaglandin endoperoxide synthase and other enzymes involved in the production of arachidonic acid products (lipoxygenases and epoxygenases) ushered in a new era of research. The goal of this review is to distill a large body of work pertaining to studies of eicosanoids in the gastrointestinal tract. This review has been organized according both to functional (secretion and motility) and disease-related (inflammation, mucosal injury, and neoplasia) effects. The aim of this article is to present a clear summary of this area of gastroenterology so that future research can be directed in a logical and productive manner.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 08:45:26