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Titolo:
VISUAL HEMINEGLECT INDUCED BY UNILATERAL STRIATAL DOPAMINE DEFICIENCYIN MONKEYS
Autore:
MIYASHITA N; HIKOSAKA O; KATO M;
Indirizzi:
JUNTENDO UNIV,SCH MED,DEPT PHYSIOL,BUNKYO KU,2-1-1 HONGO TOKYO 113 JAPAN NATL INST PHYSIOL SCI,DEPT BIOL CONTROL SYST,NEURAL CONTROL LAB OKAZAKI AICHI 444 JAPAN
Titolo Testata:
NeuroReport
fascicolo: 9, volume: 6, anno: 1995,
pagine: 1257 - 1260
SICI:
0959-4965(1995)6:9<1257:VHIBUS>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
FUNCTIONAL-PROPERTIES; CAUDATE NEURONS; OCULOMOTOR FUNCTIONS; AUDITORY RESPONSES; EYE-MOVEMENTS; RHESUS-MONKEY; MPTP; EXPECTATION; BEHAVIOR; NUCLEUS;
Keywords:
VISUAL HEMINEGLECT; MPTP; MONKEY; DOPAMINE DEFICIENCY; VISUAL SEARCH; INATTENTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
N. Miyashita et al., "VISUAL HEMINEGLECT INDUCED BY UNILATERAL STRIATAL DOPAMINE DEFICIENCYIN MONKEYS", NeuroReport, 6(9), 1995, pp. 1257-1260

Abstract

UNILATERAL dopamine deficiency of the basal ganglia produced a profound impairment of visual search. Dopaminergic innervation of the monkeystriatum was deprived unilaterally by infusing 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) into the caudate nucleus. The monkeys were shown a mirror in which they saw their own image and surroundings. Compared with the concentric and symmetrical distribution of visual search before MPTP infusion, the gaze after MPTP infusion was confined and sometimes frozen in peripheral regions in the hemispace ipsilateralto the infusion; the contralateral side was largely neglected. An experiment using a choice saccade task indicated that the contralateral visual signal, which alone was processed normally, was suppressed by the ipsilateral signal.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 18:50:19