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Titolo:
PROGESTERONE INHIBITION OF THE DEVELOPMENT OF THE LUTEOLYTIC SIGNAL IN COWS
Autore:
MANN GE; LAMMING GE;
Indirizzi:
UNIV NOTTINGHAM,DEPT PHYSIOL & ENVIRONM SCI LOUGHBOROUGH LE12 5RD LEICS ENGLAND
Titolo Testata:
Journal of Reproduction and Fertility
fascicolo: 1, volume: 104, anno: 1995,
pagine: 1 - 5
SICI:
0022-4251(1995)104:1<1:PIOTDO>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
OVARIECTOMIZED EWES; PREGNANCY RATES; HORMONE; CATTLE; PROSTAGLANDIN-F2-ALPHA; INSEMINATION; INJECTION; SECRETION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
G.E. Mann e G.E. Lamming, "PROGESTERONE INHIBITION OF THE DEVELOPMENT OF THE LUTEOLYTIC SIGNAL IN COWS", Journal of Reproduction and Fertility, 104(1), 1995, pp. 1-5

Abstract

Mated cows that subsequently undergo luteolysis have significantly lower plasma concentrations of progesterone than do cows in which pregnancy is maintained. Two groups of ovariectomized cows were treated withprogesterone and oestradiol to recreate luteal phases exhibiting the extremes of plasma concentrations of progesterone (6.0 +/- 0.4 and 12.4 +/- 0.8 ng ml(-1)) normally seen in intact cows. The effect of this difference in progesterone on the development of the luteolytic signalwas determined by monitoring the basal and oxytocin-stimulated plasmaconcentrations of the principal metabolite of prostaglandin F-2 alphaPGPM on days 12-16 of the simulated luteal phases. Basal PGFM concentrations were similar in the low and high progesterone groups on all days. The mean plasma concentration of PGFM showed a larger increase following oxytocin in the low progesterone group on days 13 and 14 (P < 0.05) and on days 15 and 16 (P < 0.1). These results demonstrate that alow plasma concentration of progesterone results in the development of a stronger luteolytic signal, and provide an explanation for the fact that cows with lower plasma concentrations of progesterone are more prone to embryo loss.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 10:33:26