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Titolo:
INITIAL MUTATIONAL STEPS TOWARD LOSS OF OPSIN GENE-FUNCTION IN CAVEFISH
Autore:
YOKOYAMA S; MEANY A; WILKENS H; YOKOYAMA R;
Indirizzi:
SYRACUSE UNIV,DEPT BIOL,BIOL RES LABS 612,130 COLL PL SYRACUSE NY 13244 UNIV HAMBURG,INST ZOOL W-2000 HAMBURG GERMANY UNIV HAMBURG,ZOOL MUSEUM W-2000 HAMBURG GERMANY
Titolo Testata:
Molecular biology and evolution
fascicolo: 4, volume: 12, anno: 1995,
pagine: 527 - 532
SICI:
0737-4038(1995)12:4<527:IMSTLO>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
FISH ASTYANAX-FASCIATUS; VISUAL PIGMENT GENES; RESTRICTION ENDONUCLEASES; DNA METHYLATION; COLOR-VISION; EVOLUTION; GREEN; SUBSTITUTION; PSEUDOGENES; CRYSTALLIN;
Keywords:
COLOR VISION; NONFUNCTIONALIZATION; CAVE FISHES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
S. Yokoyama et al., "INITIAL MUTATIONAL STEPS TOWARD LOSS OF OPSIN GENE-FUNCTION IN CAVEFISH", Molecular biology and evolution, 12(4), 1995, pp. 527-532

Abstract

The river-dwelling fishes of Astyanax fasciatus and their derivativesfrom Pachon and Micos caves in Mexico were collected. By comparing red (r007) and green (g101 and g103) opsin gene sequences from the threepopulations, we found a high frequency of C --> T changes in r007 andg103 of the eyed Micos fishes, presumably due to spontaneous cytosinemethylation or enzymatic deamination of the CG dinucleotide, and a deletion of 12 consecutive nucleotides in g101 of the blind Pachon fishes. Thus, high rates of nucleotide substitution and C --> T transitions, usually found for pseudogenes, may occur even before they become nonfunctional.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 12:47:26