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Titolo:
STATE OF AIRWAY SURFACE LIQUID ON GUINEA-PIG TRACHEA
Autore:
RAHMOUNE H; SHEPHARD KL;
Indirizzi:
UNIV BUCKINGHAM,CLORE LAB LIFE SCI BUCKINGHAM MK18 1EG ENGLAND UNIV BUCKINGHAM,CLORE LAB LIFE SCI BUCKINGHAM MK18 1EG ENGLAND
Titolo Testata:
Journal of applied physiology
fascicolo: 6, volume: 78, anno: 1995,
pagine: 2020 - 2024
SICI:
8750-7587(1995)78:6<2020:SOASLO>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPITHELIUM; TRANSPORT; FLUID; ION; INVITRO; NA+;
Keywords:
ION ACTIVITIES; EVAPORATION; CONDENSATION; MUCUS; HUMIDITY; ION-SELECTIVE MICROELECTRODES; REGULATORY PROCESSES IN THE AIRWAY; TRANSEPITHELIAL POTENTIAL DIFFERENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
H. Rahmoune e K.L. Shephard, "STATE OF AIRWAY SURFACE LIQUID ON GUINEA-PIG TRACHEA", Journal of applied physiology, 78(6), 1995, pp. 2020-2024

Abstract

Two preparations of the guinea pig trachea have been examined: an isolated preparation and a preparation in vivo, both exposed to air on the mucosal surface. Ion-selective microelectrodes have been used to measure Na (a(Na)) and K activities (a(K)) in airway surface liquid (ASL)while airflows tending either to evaporate or to condense water were applied. Other variables measured included ASL depth and transepithelial potential difference (TEPD). In isolated preparations, condensationdid not progressively alter depth, a(Na), or TEPD but caused a slightincrease in a(K). Evaporation decreased depth; increased a(Na), a(K),and osmotic pressure; and changed TEPD. Measurements on preparations in vivo broadly supported these observations. In addition, the depth of ASL developed on isolated preparations was related to the humidity of the air to which animals had been previously exposed. We conclude that condensation and evaporation at the ASL-air interface in isolated preparations and in preparations in vivo do significantly modify key ASL variables as does the relative humidity of the air to which animals are exposed before experimentation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/08/20 alle ore 23:06:13