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Titolo:
DYNAMIC ELECTROMYOGRAPHY AND MUSCLE BIOPSY CHANGES IN A 4-YEAR FOLLOW-UP - STUDY OF PATIENTS WITH A HISTORY OF POLIO
Autore:
STALBERG E; GRIMBY G;
Indirizzi:
UNIV UPPSALA HOSP,DEPT CLIN NEUROPHYSIOL S-75185 UPPSALA SWEDEN GOTHENBURG UNIV,SAHLGRENS HOSP,DEPT REHABIL MED S-41345 GOTHENBURG SWEDEN
Titolo Testata:
Muscle & nerve
fascicolo: 7, volume: 18, anno: 1995,
pagine: 699 - 707
SICI:
0148-639X(1995)18:7<699:DEAMBC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MACRO-EMG; MOTOR UNITS; POLIOMYELITIS;
Keywords:
POLIO; POSTPOLIO SYNDROME; MACRO EMG; MUSCLE BIOPSY; STRENGTH MEASUREMENTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
E. Stalberg e G. Grimby, "DYNAMIC ELECTROMYOGRAPHY AND MUSCLE BIOPSY CHANGES IN A 4-YEAR FOLLOW-UP - STUDY OF PATIENTS WITH A HISTORY OF POLIO", Muscle & nerve, 18(7), 1995, pp. 699-707

Abstract

Eighteen patients who had had polio 29-56 years prior to the first investigation were studied on two occasions, 4 years apart. Isokinetic and isometric strength measurements and Macro EMG were performed in 28 legs. Muscle biopsy specimens were obtained on both occasions from ii legs. On average the muscle strength was 56% of control values at the first examination, and decreased by another 8% during the observation period. The muscle fiber area was increased compared to that of controls and did not change significantly. Macro EMG, comprising muscle fiber area and number of muscle fibers, and/or single fi ber EMG showed clear signs of reinnervation in all legs. The motor units at the first examination were increased Ii-fold, on average, compared with age-matched control values. During the observation period, reinnervation continued and the size of motor units increased by another 56% as a result of ongoing denervation, that is, loss of neurons. This compensation wasparticularly pronounced in patients with stable conditions. The parameters studied did not reveal any definite pattern predicting future development of new muscle weakness in individual subjects. (C) 1995 JohnWiley and Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:21:56