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Titolo:
GLIOMAS - CORRELATION OF MAGNETIC-SUSCEPTIBILITY ARTIFACT WITH HISTOLOGIC GRADE
Autore:
BAGLEY LJ; GROSSMAN RI; JUDY KD; CURTIS M; LOEVNER LA; POLANSKY M; DETRE J;
Indirizzi:
THOMAS JEFFERSON UNIV HOSP,DEPT PATHOL,11TH ST & WALNUT ST PHILADELPHIA PA 19107 UNIV PENN,MED CTR,DEPT RADIOL PHILADELPHIA PA 19104 UNIV PENN,MED CTR,DEPT NEUROSURG PHILADELPHIA PA 19104 UNIV PENN,MED CTR,DEPT PATHOL PHILADELPHIA PA 19104 UNIV PENN,MED CTR,DEPT NEUROL PHILADELPHIA PA 19104 ALLEGHENY UNIV HLTH SCI,SCH PUBL HLTH PHILADELPHIA PA 19102
Titolo Testata:
Radiology
fascicolo: 2, volume: 202, anno: 1997,
pagine: 511 - 516
SICI:
0033-8419(1997)202:2<511:G-COMA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSFERRIN RECEPTOR; EFFICACY; INVITRO; EXPRESSION; TUMORS;
Keywords:
ASTROCYTOMA; BRAIN NEOPLASMS, MR; MAGNETIC RESONANCE (MR), ARTIFACT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
L.J. Bagley et al., "GLIOMAS - CORRELATION OF MAGNETIC-SUSCEPTIBILITY ARTIFACT WITH HISTOLOGIC GRADE", Radiology, 202(2), 1997, pp. 511-516

Abstract

PURPOSE: To determine whether magnetic susceptibility artifact on magnetic resonance (MR) images can be used to grade gliomas. MATERIALS AND METHODS: Twenty-nine patients with gliomas were prospectively examined with spin-echo T1-weighted MR imaging without and with contrast material enhancement, spin-echo or fast spin-echo T2- and proton-density-weighted MR imaging, and gradient-echo T2-weighted MR imaging. Imageswere reviewed by two neuroradiologists, and susceptibility artifacts in the tumor region were graded. Heterogeneity, mass effect, contrast enhancement, and necrosis were also graded. Tumors were graded according to the World Health Organization classification. RESULTS: Increasedsusceptibility artifact was detected by at least one observer on gradient-echo MR images of 19 tumors. This feature was seen on only 10 of the spin-echo or fast spin-echo T2-weighted MR images of lesions. Fifteen neoplasms with increased susceptibility artifact detected on MR images by at least one observer were high-grade lesions (anaplastic astrocytoma or glioblastoma multiforme). Lesion susceptibility artifact detected on T2-weighted MR images was associated with tumor grade (P < .05). CONCLUSION: Susceptibility artifacts on T2-weighted gradient-echo MR images appear to be valuable in the preoperative evaluation of gliomas.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 00:47:44