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Titolo:
EFFECT OF DIFFERENT VOLATILE ANESTHETICS ON SUXAMETHONIUM-INDUCED JAWMUSCLE CONTRACTURE IN RATS
Autore:
SHI Y; KEYKHAH MM; STORELLA RJ; ROSENBERG H;
Indirizzi:
HAHNEMANN UNIV,DEPT ANESTHESIOL PHILADELPHIA PA 19102
Titolo Testata:
British Journal of Anaesthesia
fascicolo: 6, volume: 74, anno: 1995,
pagine: 712 - 713
SICI:
0007-0912(1995)74:6<712:EODVAO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPERTHERMIA;
Keywords:
ANESTHETICS VOLATILE, HALOTHANE; ANESTHETICS VOLATILE, ISOFLURANE; ANESTHETICS VOLATILE, DESFLURANE; NEUROMUSCULAR BLOCK, SUXAMETHONIUM; TEMPERATURE, EFFECT;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
5
Recensione:
Indirizzi per estratti:
Citazione:
Y. Shi et al., "EFFECT OF DIFFERENT VOLATILE ANESTHETICS ON SUXAMETHONIUM-INDUCED JAWMUSCLE CONTRACTURE IN RATS", British Journal of Anaesthesia, 74(6), 1995, pp. 712-713

Abstract

Previous work has demonstrated that the interaction of hyperthermia and halothane may greatly increase the jaw muscle contracture produced by suxamethonium. We have compared the interaction of temperature and suxamethonium in the presence of halothane with the suxamethonium/temperature interaction of two other volatile anaesthetics, isoflurane anddesflurane. Rats were anaesthetized with 1.35 MAC of halothane, isoflurane or desflurane. The jaw area was heated to 36-41 degrees C by a heating lamp while rectal temperature was maintained at 37 degrees C. Isometric tension was recorded from the jaw muscles. Suxamethonium 750 mu g kg(-1) i.v. induced a transient jaw muscle contracture (JMC) during halothane, isoflurane and desflurane anaesthesia. JMC exhibited significant dependence on jaw muscle temperature with all three volatile anaesthetics. Increasing the temperature of the jaw area from 37 degrees C to 41 degrees C increased JMC 8.7-fold with halothane, 8.8-fold with isoflurane and 3.1-fold with desflurane. The difference between halothane and desflurane was significant. While suxamethonium-induced JMC was dependent on temperature for all three volatile anaesthetic, thetemperature dependence appeared to be less with desflurane.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:51:12