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Titolo:
COMBINED ENDOBRONCHIAL AND CONVENTIONAL T HERAPY OF INOPERABLE CENTRAL LUNG-CANCER
Autore:
BOLLIGER CT; SOLER M; TAMM M; PERRUCHOUD AP;
Indirizzi:
KANTONSSPITAL,DEPT INNERE MED,PNEUMOL ABT,PETERSGRABEN 4 CH-4031 BASEL SWITZERLAND
Titolo Testata:
Schweizerische medizinische Wochenschrift
fascicolo: 21, volume: 125, anno: 1995,
pagine: 1052 - 1059
SICI:
0036-7672(1995)125:21<1052:CEACTH>2.0.ZU;2-A
Fonte:
ISI
Lingua:
GER
Soggetto:
SMALL-CELL-CARCINOMA; YAG LASER PHOTORESECTION; RADIATION-THERAPY; TRACHEOBRONCHIAL STENOSES; BRONCHOGENIC-CARCINOMA; THORACIC RADIOTHERAPY; 5-YEAR EXPERIENCE; SILICONE STENTS; ONCOLOGY-GROUP; IRRADIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
C.T. Bolliger et al., "COMBINED ENDOBRONCHIAL AND CONVENTIONAL T HERAPY OF INOPERABLE CENTRAL LUNG-CANCER", Schweizerische medizinische Wochenschrift, 125(21), 1995, pp. 1052-1059

Abstract

Up to 85% of patients with bronchogenic carcinoma are inoperable at the time of diagnosis and treatment remains largely palliative. Prognosis depends on the clinical tumor stage. In non-small cell carcinoma the clinical stages (I-IV) are defined according to the TNM classification, whereas in small cell carcinoma limited disease is distinguished from extensive disease. Neither classification accurately takes endobronchial tumor spread into account. At the time of diagnosis up to 30% of all lung cancer patients present with central airway obstruction andclinical signs of dyspnea, atelectasis and pneumonia. Most patients with central airway stenosis have inoperable tumors (stage IIIb and IV)and have until recently undergone conventional treatment consisting exclusively of chemo- and radiotherapy. Currently the best results are obtained with combined chemoradiotherapy. The rapid developments in the area of endobronchial treatment modalities enable us to relieve bronchial obstructions fast and safely. This achieves immediate symptomatic relief which in many cases is a precondition for starting chemo- or radiotherapy. Successful reopening of a major airway helps to prolong local tumor control and thus survival. Patients with inoperable lung cancer and obstruction of central airways should undergo initial endobronchial therapy followed by conventional chemo-radiotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 20:27:07