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Titolo:
BONE INDUCTION OF HYDROXYAPATITE COMBINED WITH BONE MORPHOGENETIC PROTEIN AND COVERED WITH PERIOSTEUM
Autore:
ONO I; GUNJI H; SUDA K; KANEKO F; MURATA M; SAITO T; KUBOKI Y;
Indirizzi:
FUKUSHIMA MED COLL,DEPT DERMATOL,DIV PLAST & RECONSTRUCT SURG,HIKARIGAOKA-1 FUKUSHIMA 96012 JAPAN HOKKAIDO UNIV,SCH DENT,DEPT ORAL SURG 2 SAPPORO HOKKAIDO 060 JAPAN HOKKAIDO UNIV,SCH DENT,DEPT BIOCHEM SAPPORO HOKKAIDO 060 JAPAN
Titolo Testata:
Plastic and reconstructive surgery
fascicolo: 7, volume: 95, anno: 1995,
pagine: 1265 - 1272
SICI:
0032-1052(1995)95:7<1265:BIOHCW>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERIODONTAL OSSEOUS DEFECTS; GRAFT SUBSTITUTE; POROUS HYDROXYAPATITE; CORALLINE HYDROXYAPATITE; ORTHOGNATHIC SURGERY; CALVARIAL DEFECTS; ADULT PRIMATES; HYDROXYLAPATITE; AUGMENTATION; OSTEOGENIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
I. Ono et al., "BONE INDUCTION OF HYDROXYAPATITE COMBINED WITH BONE MORPHOGENETIC PROTEIN AND COVERED WITH PERIOSTEUM", Plastic and reconstructive surgery, 95(7), 1995, pp. 1265-1272

Abstract

Using a rabbit model, we evaluated the role of the peirosteum in boneinduction using hydroxyapatite ceramic pellets, some of which had been coated with bone morphogenetic protein. Eighteen rabbits were divided into two groups, a control group that received pellets soaked in phosphate-buffered saline alone and another group for which the pellets had been supplemented with bone morphogenetic protein. After making a skin incision on the head of each rabbit, two caudally pedicled periosteal flaps measuring 1 cm in width and 2.5 cm in length were elevated. These flaps were wrapped around hydroxyapatite pellets manufactured from limestone and fixed with sutures. After implantation, both groups of rabbits were returned to their cages, maintained for 3, 6, or 9 weeks [every group consisted of 3 rabbits (6 pellets)], and then sacrificed. In this study, the extent of bone induction, which was measured with a dual x-ray densitometer, that resulted from covering the hydroxyapatite pellet with periosteum alone (control group) was minimal. On thecontrary,since osteogenesis from the periosteum toward the pores Of the pellet was observed in the bone morphogenetic protein group much more than in the control group, the usefulness of our technique was confirmed. However, active osteogenesis was observed with subperiosteal implantation of the hydroyvapatite-bone morphogenetic protein complex inthe bone morphogenetic protein group, but the osteogenesis observed was not distributed over the entire pellet.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 21:06:11