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Titolo:
GROWTH OF THE CRANIAL VAULT IN RABBITS WITH CONGENITAL CORONAL SUTURESYNOSTOSIS
Autore:
BURROWS AM; MOONEY MP; SMITH TD; LOSKEN HW; SIEGEL MI;
Indirizzi:
UNIV PITTSBURGH,DEPT ANTHROPOL,3H01 FORBES QUAD PITTSBURGH PA 15260 UNIV PITTSBURGH,DEPT ANAT & HISTOL PITTSBURGH PA 15260 UNIV PITTSBURGH,DEPT PLAST SURG,DIV PLAST & RECONSTRUCT SURG PITTSBURGH PA 15260 CLEFT PALATE CRANIOFACIAL CTR,MED SERV PITTSBURGH PA 00000 CHILDRENS HOSP PITTSBURGH PITTSBURGH PA 15213
Titolo Testata:
The Cleft palate-craniofacial journal
fascicolo: 3, volume: 32, anno: 1995,
pagine: 235 - 246
SICI:
1055-6656(1995)32:3<235:GOTCVI>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CRANIOSYNOSTOSIS; DEFORMATION; COMPLEXITY;
Keywords:
CORONAL SUTURE; CRANIAL VAULT; CRANIOFACIAL GROWTH; CRANIOSYNOSTOSIS; MIDDLE MENINGEAL ARTERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Burrows et al., "GROWTH OF THE CRANIAL VAULT IN RABBITS WITH CONGENITAL CORONAL SUTURESYNOSTOSIS", The Cleft palate-craniofacial journal, 32(3), 1995, pp. 235-246

Abstract

Craniofacial growth data from craniosynostotic children have shown that suture immobilization results in predictable restrictions of cranial vault growth in a direction perpendicular to the affected suture andcompensatory growth at sutures perpendicular to the affected one, This study tests these predictions by using rabbits with nonsyndromic congenital coronal suture synostosis, Data were collected from 96 rabbitsdivided into three groups: 42 unaffected litter mate controls, 33 partially synostosed rabbits, and 21 completely synostosed rabbits, Markers were placed bilaterally on either side of the vault sutures at 1.5 weeks of age, Serial radiographs were taken at 1.5, 6, 12, and 18 weeks of age for assessment of growth at the vault sutures and of various cranial landmarks, Results revealed that completely synostosed animalshad significantly (p < .05) shorter cranial vaults, reduced growth atthe coronal suture, and increased growth at the sagittal, frontal, and squamosal sutures compared with unaffected rabbits. Results also showed that the calvarial growth observed in this craniosynostotic rabbitmodel closely reflects predicted compensatory patterns seen in human clinical populations and that this rabbit model is valuable for understanding the pathogeneses and craniofacial growth patterns of humans with premature cranial suture synostosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:06:29