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Titolo:
ONSET AND DEVELOPMENT OF AUDITORY BRAIN-STEM RESPONSES IN THE MONGOLIAN GERBIL (MERIONES-UNGUICULATUS)
Autore:
MCFADDEN SL; WALSH EJ; MCGEE J;
Indirizzi:
BOYS TOWN NATL RES HOSP,DEV AUDITORY PHYSIOL LAB,555 N 30TH ST OMAHA NE 68131 BOYS TOWN NATL RES HOSP,DEV AUDITORY PHYSIOL LAB OMAHA NE 68131
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 100, anno: 1996,
pagine: 68 - 79
SICI:
0378-5955(1996)100:1-2<68:OADOAB>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE-EAR DEVELOPMENT; OUTER HAIR-CELLS; POSTNATAL-DEVELOPMENT; COCHLEAR FUNCTION; NEONATAL GERBIL; SENSITIVITY; POTENTIALS; ONTOGENY;
Keywords:
AUDITORY EVOKED POTENTIAL; THRESHOLD SENSITIVITY; AUDITORY DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
S.L. Mcfadden et al., "ONSET AND DEVELOPMENT OF AUDITORY BRAIN-STEM RESPONSES IN THE MONGOLIAN GERBIL (MERIONES-UNGUICULATUS)", Hearing research, 100(1-2), 1996, pp. 68-79

Abstract

The ontogeny of auditory function in the Mongolian gerbil (Meriones unguiculatus) was examined by measuring auditory brainstem response (ABR) thresholds for clicks and tone bursts at frequencies between 0.125 and 32 kHz. ABRs were elicited as early as 10 postnatal days (PND) in a small proportion of animals (28.6%). Three phases of development were identified based on the appearance of frequency-threshold curves: (a) an onset period (10-12 PND) during which ABRs could be elicited onlyby intense stimuli (95-110 dB SPL) within a restricted range of frequencies (0.25-8 kHz); (b) a transition period (13-14 PND) during which thresholds improved but frequency-threshold curves remained relativelyflat; and (c) a refinement period (15-30 PND) during which frequency-threshold curves exhibited an adult-like ('V') shape and thresholds improved steadily to adult-like values. Opening of the external auditorymeatus was associated with threshold improvements but not with changes in the frequency region of greatest sensitivity. Between the ages of13 and 21 PND, low-frequency (0.125-1 kHz) and high-frequency (10-32 kHz) thresholds improved at statistically equivalent rates (4.9 and 5.6 dB/day, respectively), while thresholds for mid-frequency stimuli (2-8 kHz) improved at a significantly faster rate of 9.2 dB/day.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 14:43:45