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Titolo:
INEXPENSIVE CONTINUOUS-INFUSION SWIVEL - TOWARDS MORE PHYSIOLOGICAL MEASUREMENTS
Autore:
FRUHBECK G;
Indirizzi:
UNIV NAVARRA,SCH MED,DEPT PHYSIOL E-31080 PAMPLONA SPAIN
Titolo Testata:
Physiological Research
fascicolo: 2, volume: 44, anno: 1995,
pagine: 121 - 126
SICI:
0862-8408(1995)44:2<121:ICS-TM>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADULT MALE-RATS; STRESS; PROLACTIN; ETHER; YOUNG;
Keywords:
RAT; ETHER STRESS; RESTRAINT STRESS; INFUSION EXPERIMENTS; DISPOSABLE EQUIPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
G. Fruhbeck, "INEXPENSIVE CONTINUOUS-INFUSION SWIVEL - TOWARDS MORE PHYSIOLOGICAL MEASUREMENTS", Physiological Research, 44(2), 1995, pp. 121-126

Abstract

A cheap, simple and fast procedure of building an infusion swivel is described for both short- and long-term experiments in rats. To assemble the swivel, plastic laboratory syringe elements, needles and a three-way stopcock are used. The swivel avoids cannula-kinking and permitsanimals free movement inside the cage. In addition, the gadget presented is inexpensive enough to make it disposable. Further advantages ofthe self-made infusion swivel depend on its disposability, it is time-saving, simplifies blood sampling or administration of drugs and prevents contamination, when using radiolabelled products. The haemodynamics and metabolism of rat subjected to restraint stress or ether-anaesthetized rats significantly differ from those of conscious freely moving animals. Whereas restraint stress provoked a more pronounced increase of blood pressure and heart rate, ether anaesthesia induced a 19 % rise in serum glucose. Thus, the device described in this study provides more physiological experimental conditions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 09:56:26