Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
QUANTITATIVE CHEST COMPUTED-TOMOGRAPHY AS A MEANS OF PREDICTING EXERCISE PERFORMANCE IN SEVERE EMPHYSEMA
Autore:
CRAUSMAN RS; FERGUSON G; IRVIN CG; MAKE B; NEWELL JD;
Indirizzi:
NATL JEWISH CTR IMMUNOL & RESP MED,DEPT RADIOL,1400 JACKSON ST DENVERCO 80206 NATL JEWISH CTR IMMUNOL & RESP MED,DEPT RADIOL DENVER CO 80206 NATL JEWISH CTR IMMUNOL & RESP MED,DEPT MED DENVER CO 80206 UNIV COLORADO,HLTH SCI CTR,DIV PULM SCI & CRIT CARE MED DENVER CO 00000 UNIV COLORADO,HLTH SCI CTR,DEPT RADIOL DENVER CO 80262
Titolo Testata:
Academic radiology
fascicolo: 6, volume: 2, anno: 1995,
pagine: 463 - 469
SICI:
1076-6332(1995)2:6<463:QCCAAM>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-RESOLUTION CT; PULMONARY-FUNCTION TESTS; DIFFUSING-CAPACITY; LUNG DENSITY; DIAGNOSIS; DISEASE; SMOKERS;
Keywords:
EMPHYSEMA; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; PULMONARY REHABILITATION; QUANTITATIVE CHEST COMPUTED TOMOGRAPHY; EXERCISE TESTING AND CIGARETTE SMOKING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
R.S. Crausman et al., "QUANTITATIVE CHEST COMPUTED-TOMOGRAPHY AS A MEANS OF PREDICTING EXERCISE PERFORMANCE IN SEVERE EMPHYSEMA", Academic radiology, 2(6), 1995, pp. 463-469

Abstract

Rationale and Objectives. We assessed the value of quantitative high-resolution computed tomography (CT) as a diagnostic and prognostic tool in smoking-related emphysema. Methods. We performed an inception cohort study of 14 patients referred with emphysema. The diagnosis of emphysema was based on a compatible history, physical examination, chest radiograph, CT scan of the lung, and pulmonary physiologic evaluation. Results. As a group, those who underwent exercise testing were hyperinflated (percentage predicted total lung capacity +/- standard error of the mean = 133 +/- 9%), and there was evidence of air trapping (percentage predicted respiratory volume = 318 I 31%) and airflow limitation (forced expiratory volume in 1 sec [FEV1] = 40 +/- 7%). The exerciseperformance of the group was severely limited (maximum achievable workload = 43 +/- 6%) and was characterized by prominent ventilatory, gasexchange, and pulmonary vascular abnormalities. The quantitative CT index was markedly elevated in all patients (76+/-9; n=14; normal < 4). There were correlations between this quantitative CT index and measures of airflow limitation (FEV1 r(2)=.34, p=.09; FEV1/forced vital capacity r(2) = .46, p = .04) and between maximum workload achieved (r(2) = .93, p = .0001) and maximum oxygen utilization (r(2)=.83, p=.0007). Conclusion. Quantitative chest CT assessment of disease severity is correlated with the degree of airflow limitation and exercise impairmentin pulmonary emphysema.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 16:28:57