Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
OXYTOCIN-INDUCED PROSTAGLANDIN-F2-ALPHA RELEASE AND ENDOMETRIAL OXYTOCIN RECEPTOR CONCENTRATIONS THROUGHOUT PREGNANCY IN EWES
Autore:
MEIER S; LAU TM; JENKIN G; FAIRCLOUGH RJ;
Indirizzi:
MONASH UNIV,DEPT PHYSIOL CLAYTON VIC 3168 AUSTRALIA MONASH UNIV,DEPT PHYSIOL CLAYTON VIC 3168 AUSTRALIA VICTORIAN INST ANIM SCI WERRIBEE VIC 3030 AUSTRALIA
Titolo Testata:
Journal of Reproduction and Fertility
fascicolo: 2, volume: 103, anno: 1995,
pagine: 233 - 238
SICI:
0022-4251(1995)103:2<233:OPRAEO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROUS-CYCLE; OVARIECTOMIZED EWES; PULSATILE SECRETION; OVINE ENDOMETRIUM; OVARIAN OXYTOCIN; PROGESTERONE; SHEEP; BINDING; ESTRADIOL; PROTEIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
S. Meier et al., "OXYTOCIN-INDUCED PROSTAGLANDIN-F2-ALPHA RELEASE AND ENDOMETRIAL OXYTOCIN RECEPTOR CONCENTRATIONS THROUGHOUT PREGNANCY IN EWES", Journal of Reproduction and Fertility, 103(2), 1995, pp. 233-238

Abstract

Endometrial oxytocin receptor concentrations and oxytocin-induced plasma concentrations of 13,14,dihydro-15-keto prostaglandin F-2 alpha were investigated on days 14 and 17 of the oestrous cycle and on days 14, 17, 25, 65, 85 and 145 of gestation in ewes. Total 13,14,dihydro-15-keto prostaglandin F-2 alpha release in response to a bolus injection of oxytocin was significantly (P < 0.05) higher at luteolysis (day 17 of the oestrous cycle) than at any other stage of the oestrous cycle or in early gestation. On days 65, 85 and 145 of gestation, total prostaglandin release was significantly (P < 0.05) increased compared with earlier in gestation. Maximum concentrations of 13,14,dihydro-15-keto prostaglandin F-2 alpha in response to oxytocin followed a similar pattern. Oxytocin receptor concentrations reflected total oxytocin-induced 13, 14,dihydro-15-keto prostaglandin F-2 alpha release, with increased oxytocin receptor concentrations occurring on day 17 of the oestrous cycle, compared with those observed on day 14 of the oestrous cycle and on days 14, 17 and 25 of gestation. By day 65 of gestation, oxytocin receptor concentrations were again increased. However, on days 85 and 145 of gestation, oxytocin receptor concentrations had decreased toconcentrations similar to those observed in early gestation. These results indicate that oxytocin-induced 13,14,dihydro-15-keto prostaglandin F-2 alpha release during early gestation is minimal despite the presence of endometrial oxytocin receptors. In mid-gestation, ocytocin-stimulated 13,14,dihydro-15-keto prostaglandin F-2 alpha release is increased with a concomitant increase in uterine oxytocin receptor concentrations. However, by the later stages of gestation, oxytocin receptor concentrations, but not oxytocin-stimulated 13,14,dihydro-15-keto prostaglandin F-2 alpha release, were again decreased. Thus, there appearsto be a dissociation between the response to oxytocin and endometrialoxytocin concentrations at specific stages of the reproductive cycle in sheep.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 01:27:07