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Titolo:
CLEAR-CELL (SUGAR) TUMOR OF THE LUNG IS A LESION STRICTLY RELATED TO ANGIOMYOLIPOMA - THE CONCEPT OF A FAMILY OF LESIONS CHARACTERIZED BY THE PRESENCE OF THE PERIVASCULAR EPITHELIOID CELLS (PEG)
Autore:
BONETTI F; PEA M; MARTIGNONI G; DOGLIONI C; ZAMBONI G; CAPELLI P; RIMONDI P; ANDRION A;
Indirizzi:
UNIV VERONA,POLICLIN BORGO ROMA,IST ANAT PATOL I-37134 VERONA ITALY UNIV VERONA,OSPED CIVILE FELTRE,IST ANAT PATOL I-37100 VERONA ITALY OSPED CIVILE ASTI ASTI ITALY OSPED CIVILE ROVIGO ROVIGO ITALY
Titolo Testata:
Pathology
fascicolo: 3, volume: 26, anno: 1995,
pagine: 230 - 236
SICI:
0031-3025(1995)26:3<230:C(TOTL>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONOCLONAL-ANTIBODY; LYMPHANGIOMYOMATOSIS; MELANOCYTES; CARCINOMA; MELANOMA; HMB-45; HMB45;
Keywords:
SUGAR TUMOR; ANGIOMYOLIPOMA; MELANOGENESIS; MELANOMA-ASSOCIATED ANTIGENS; TUBEROUS SCLEROSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
F. Bonetti et al., "CLEAR-CELL (SUGAR) TUMOR OF THE LUNG IS A LESION STRICTLY RELATED TO ANGIOMYOLIPOMA - THE CONCEPT OF A FAMILY OF LESIONS CHARACTERIZED BY THE PRESENCE OF THE PERIVASCULAR EPITHELIOID CELLS (PEG)", Pathology, 26(3), 1995, pp. 230-236

Abstract

We report a comparative study of 3 clear cell tumors of the lung (CCTL) and 3 angiomyolipomas (AML) of the kidney. Morphological analysis shows that the cells of CCTL are identical to the perivascular epithelioid component of AML. Phenotypically they both consistently expressed melanoma-associated antigens recognized by Moabs HMB45 and HMSA-1, while they were negative for HMSA-5. A minority of cells also expressed S-100 protein, vimentin and actin. In addition, one case of CCTL showedmature adipose tissue entrapped in the proliferation, thus suggestingan intermediate form between CCTL and AML. Based on morphological andphenotypical similarities, it is suggested that CCTL and AML belong to the same family of lesions, characterized by the presence of a peculiar muscle cell, expressing different melanoma-associated antigens.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 08:27:57