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Titolo:
MONOLAYER-CULTURE CONDITIONS SUITABLE FOR PRIMITIVE ERYTHROID CELL-DIFFERENTIATION FROM EMBRYONIC STEM-CELLS IN-VITRO
Autore:
ATSUMI T; NAGAYOSHI M; ANZAI H; IKAWA Y;
Indirizzi:
INST PHYS & CHEM RES,TSUKUBA LIFE SCI CTR,ONCOL MOLEC LAB,3-1-1 KOYADAI TSUKUBA IBARAKI 305 JAPAN
Titolo Testata:
Development, growth & differentiation
fascicolo: 2, volume: 37, anno: 1995,
pagine: 167 - 172
SICI:
0012-1592(1995)37:2<167:MCSFPE>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM-FREE MEDIUM; MOUSE TERATOCARCINOMA; INVITRO; PCC3/A/1;
Keywords:
BLOOD ISLAND; EMBRYONIC STEM CELL; LIF; MESODERMAL DIFFERENTIATION; PRIMITIVE ERYTHROID CELL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
T. Atsumi et al., "MONOLAYER-CULTURE CONDITIONS SUITABLE FOR PRIMITIVE ERYTHROID CELL-DIFFERENTIATION FROM EMBRYONIC STEM-CELLS IN-VITRO", Development, growth & differentiation, 37(2), 1995, pp. 167-172

Abstract

Embryonic stem (ES) cells effectively differentiated into primitive erythroid/mesodermal cells when grown in the absence of both a feeder layer and leukemia inhibitory factor (LIF). The formation of a three-dimensional structure, exogenous mesoderm induction factors and exogenous hematopoietic growth factors were not essential for their differentiation. Primitive erythroid cells were first detected on day 5 in the differentiation-permissive cultures. Differentiation into other mesodermal cells was always preceded by that into primitive erythroid cells. Precursor cells of erythroid cells but of other hematoid cells were also detected in this system. This model system is useful for studying the early steps of mesoderm formation in mouse embryogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 01:57:11