Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
GENETIC-POLYMORPHISM (ARG353-]GLN) IN COAGULATION-FACTOR-VII GENE ANDFACTOR-VII LEVELS (COAGULANT ACTIVITY, ANTIGEN AND BINDING ABILITY TOTISSUE FACTOR) IN 101 HEALTHY JAPANESE
Autore:
TAKAMIYA O;
Indirizzi:
SHINSHU UNIV,SCH ALLIED MED SCI,DEPT MED TECHNOL,3-1-1 MATSUMOTO ASAHI 390 JAPAN
Titolo Testata:
Scandinavian journal of clinical & laboratory investigation
fascicolo: 3, volume: 55, anno: 1995,
pagine: 211 - 215
SICI:
0036-5513(1995)55:3<211:G(ICGA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; CARDIOVASCULAR-DISEASE; HEART-DISEASE; RISK; VARIANTS; PLASMA; MEN;
Keywords:
BINDING ABILITY OF FACTOR VII TO TISSUE FACTOR; FACTOR VII ACTIVITY; FACTOR VII ANTIGEN; GENETIC POLYMORPHISM; JAPANESE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
O. Takamiya, "GENETIC-POLYMORPHISM (ARG353-]GLN) IN COAGULATION-FACTOR-VII GENE ANDFACTOR-VII LEVELS (COAGULANT ACTIVITY, ANTIGEN AND BINDING ABILITY TOTISSUE FACTOR) IN 101 HEALTHY JAPANESE", Scandinavian journal of clinical & laboratory investigation, 55(3), 1995, pp. 211-215

Abstract

We studied the frequency of the Msp I genotype (Gln353) for factor VII in 101 young healthy Japanese individuals, and the levels of factor VII-related procoagulant activity (FVII:c), antigen (FVII:ag) and binding ability to tissue factor (FVII-TF binding). The frequency of the allele coding for the factor VII Gln353 was 0.05 among this group. Individuals with genotype M1M1 had an FVII:c of 103.52 +/- 17.85% (mean +/- SD), FVII:ag of 102.50 +/- 18.42% (mean +/- SD) and FVII-TF binding of 101.03 +/- 22.22% (mean +/- SD). Triglyceride levels of subjects with the M1M1 genotype were 84.34 +/- 44.97 mg dl(-1) (mean +/- SD). FVII:c (50%), FVII:ag (45%) and FVII-TF binding (36%) from an individual with the M2M2 type was the lowest, with a triglyceride value of 39 mg dl(-1). On the other hand, individuals with the genotype M1M2 had an FVII:c of 75.57 +/- 9.61% (mean +/- SD), FVII:ag of 72.43 +/- 8.54% (mean +/- SD) and FVII-TF binding of 68.14 +/- 14.91% (mean +/- SD). FVII:c, FVII:ag and FVII-TF binding in individuals with the M1M2 and M2M2 genotypes were significantly lower than those in individuals with the M1M1 genotype.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 14:24:18