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Titolo:
CONTRAST SENSITIVITY IN ALZHEIMERS-DISEASE - A 1-YEAR LONGITUDINAL ANALYSIS
Autore:
GILMORE GC; WHITEHOUSE PJ;
Indirizzi:
CASE WESTERN RESERVE UNIV,DEPT PSYCHOL,10900 EUCLID AVE CLEVELAND OH 44106
Titolo Testata:
Optometry and vision science
fascicolo: 2, volume: 72, anno: 1995,
pagine: 83 - 91
SICI:
1040-5488(1995)72:2<83:CSIA-A>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Keywords:
CONTRAST SENSITIVITY; ALZHEIMERS DISEASE; LONGITUDINAL; M AND P CHANNELS; INCREASING CONTRAST; NICOLET; VISTECH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
G.C. Gilmore e P.J. Whitehouse, "CONTRAST SENSITIVITY IN ALZHEIMERS-DISEASE - A 1-YEAR LONGITUDINAL ANALYSIS", Optometry and vision science, 72(2), 1995, pp. 83-91

Abstract

Spatial contrast sensitivity was evaluated in normal elderly adults and a group with probable Alzheimer's disease (AD) in three sessions over a 1-year period. There was evidence of a reduction over 1 year in contrast sensitivity for static, high spatial frequencies in both groups of subjects. A striking difference between the subject groups was observed in their response to flickered stimuli. Although normal elderlyadults yielded good stability in sensitivity for both static and flickered spatial frequencies over the 1 year, AD patients experienced a significant decline in response to flickered (7.5 Hz) stimuli. The significant decline in sensitivity for low contrast, high temporal events in AD patients is consistent with reports of cell loss at the retinal and cortical levels of the magnocellular (M) channel in AD. Thus, the spatial contrast sensitivity change in AD may reflect a more rapid loss of cells specifically in the M channel over a 1-year period.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:56:20