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Titolo:
MODIFIED RT-PA PULSE-SPRAY-LYSIS BY HAND FOR TREATMENT OF OCCLUDED LEG ARTERIES AND FEMOROPOPLITEAL BYPASS GRAFTS
Autore:
MULLERHULSBECK S; SCHWARZENBERG H; LINK J; WALLUSCHECK K; BROSSMANN J; REGENSBURGER D; HELLER M;
Indirizzi:
CHRISTIAN ALBRECHTS UNIV KIEL,RADIOL DIAGNOST KLIN,ARNOLD HELLER STR 9 D-24105 KIEL GERMANY CHRISTIAN ALBRECHTS UNIV KIEL,KLIN HERZ & GEFASSCHIRURG D-24105 KIEL GERMANY
Titolo Testata:
RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren
fascicolo: 6, volume: 165, anno: 1996,
pagine: 557 - 562
SICI:
0936-6652(1996)165:6<557:MRPBHF>2.0.ZU;2-G
Fonte:
ISI
Lingua:
GER
Soggetto:
PERIPHERAL ARTERIAL; PLASMINOGEN-ACTIVATOR; THROMBOLYTIC THERAPY; INTRAARTERIAL THROMBOLYSIS; OCCLUSIONS; INFUSION; FIBRINOLYSIS; EFFICACY;
Keywords:
PERIPHERAL ARTERY OCCLUSIVE VESSEL DISEASE; LOCAL RT-PA PULSE-SPRAY-LYSIS; KATZEN(R) INFUSION WIRE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
S. Mullerhulsbeck et al., "MODIFIED RT-PA PULSE-SPRAY-LYSIS BY HAND FOR TREATMENT OF OCCLUDED LEG ARTERIES AND FEMOROPOPLITEAL BYPASS GRAFTS", RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 165(6), 1996, pp. 557-562

Abstract

Purpose: The evaluation of local rt-PA pulse-spray-lysis (PSL) by theKatzen(R) infusion wire for treatment of thrombosed leg arteries and bypass grafts. Material and method: 21 patients (mean age 64.4 years) with either occluded leg arteries (n = 19) or femorocrural bypass grafts (n = 2) were treated with PSL. Mean length of occlusion was 13.2 +/- 11.6 cm. Time of occlusion ranged from less than one week to 6 months. Results: In 71.43% (15/21) the occlusions could be successfully recanalized with PSl. The mean rt-PA dose was 10.7 +/- 4.9 mg. Remaining stenoses were handled with PTA (n = 9) and additional stent implantation (n = 3). Additional long-time-lysis with 17.5 mg rt-PA was necessary in two cases, the success rate increased to 81% (17/21). The ankle-brachial-index increased from 0.38 +/- 0.29 to 0.83 +/- 0.32 within 24 hours after intervention. In 4 cases bleeding complications occurred. 5 patients showed reocclusions during 6 months follow-up. Conclusions:Local fibrinolysis with rt-PA in PSL technique using the Katzen(R) infusion wire is a feasible and promising treatment of thrombosed leg arteries and grafts. Even careful and dosage-minimized rt-PA applicationcannot prevent bleeding complications.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 14:28:09