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Titolo:
EVALUATION OF OUTCOME OF DELAYED NEUROLOGIC SEQUELAE AFTER CARBON-MONOXIDE POISONING BY TC-99M HEXAMETHYLPROPYLENE AMINE OXIME BRAIN SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY
Autore:
CHOI IS; KIM SK; LEE SS; CHOI YC;
Indirizzi:
YONSEI UNIV,YONGDONG SEVERANCE HOSP,COLL MED,DEPT NEUROL,146-92 DOGOKDONG SEOUL 135270 SOUTH KOREA
Titolo Testata:
European neurology
fascicolo: 3, volume: 35, anno: 1995,
pagine: 137 - 142
SICI:
0014-3022(1995)35:3<137:EOOODN>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; INTERVAL FORM; INTOXICATION; FEATURES; OXYGEN; CT;
Keywords:
OUTCOME; DELAYED NEUROLOGIC SEQUELAE; CARBON MONOXIDE POISONING; TC-99M HEXAMETHYLPROPYLENE; AMINE OXIME; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
I.S. Choi et al., "EVALUATION OF OUTCOME OF DELAYED NEUROLOGIC SEQUELAE AFTER CARBON-MONOXIDE POISONING BY TC-99M HEXAMETHYLPROPYLENE AMINE OXIME BRAIN SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY", European neurology, 35(3), 1995, pp. 137-142

Abstract

Using brain computed tomography (CT) and single photon emission computed tomography (SPECT) with technetium-99m hexamethylpropylene amine oxime (Tc-99m HM-PAO) in 13 patients with delayed neurologic sequelae after carbon monoxide poisoning, we tried to evaluate the clinical outcome of delayed CO sequelae. Among the 13 initial brain CTs, seven showed low density in the cerebral white matter and one revealed hypodensity in both globi pallidi. Of the 7 follow-up CT scans, 3 have remainedunchanged, but in 4 cases more aggravating patterns with cortical atrophy without the clinical correlation were observed. There was no correlation between the CT findings and the outcome of delayed CO sequelae. All initial SPECTs in 13 patients with delayed CO sequelae showed diffuse patchy hypoperfusion throughout the cerebral cortex. Among the follow-up SPECTs in 7 patients, 6 patients showed increased cerebral perfusion with the concomitant clinical improvement, but the SPECT of a patient in bedridden state had remained unchanged, compared with the initial SPECT. There seemed to be good correlation between the findingsof SPECT and the outcome of delayed CO sequelae. In conclusion, Tc-99m HM-PAO brain SPECT is more sensitive than CT, and may be a useful test in evaluating the clinical outcome of delayed neurologic sequelae after CO poisoning.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:13:03