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Titolo:
COMMUNITY STUDY OF ROLE OF VIRAL-INFECTIONS IN EXACERBATIONS OF ASTHMA IN 9-11 YEAR-OLD CHILDREN
Autore:
JOHNSTON SL; PATTEMORE PK; SANDERSON G; SMITH S; LAMPE F; JOSEPHS L; SYMINGTON P; OTOOLE S; MYINT SH; TYRRELL DAJ; HOLGATE ST;
Indirizzi:
UNIV MED SOUTHAMPTON,SOUTHAMPTON GEN HOSP SOUTHAMPTON SO9 4XY HANTS ENGLAND UNIV SOUTHAMPTON,DEPT MED STAT & COMP SOUTHAMPTON SO9 4XY HANTS ENGLAND UNIV LEICESTER,DEPT MICROBIOL LEICESTER LE1 9HN LEICS ENGLAND MRC,COMMON COLD UNIT SALISBURY WILTS ENGLAND
Titolo Testata:
BMJ. British medical journal
fascicolo: 6989, volume: 310, anno: 1995,
pagine: 1225 - 1229
SICI:
0959-8138(1995)310:6989<1225:CSOROV>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
WHEEZY BRONCHITIS; RESPIRATORY-INFECTIONS; VIRUSES; SYMPTOMS; ADULTS; PRECIPITANTS; ASSOCIATION; CORONAVIRUS; CHILDHOOD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
S.L. Johnston et al., "COMMUNITY STUDY OF ROLE OF VIRAL-INFECTIONS IN EXACERBATIONS OF ASTHMA IN 9-11 YEAR-OLD CHILDREN", BMJ. British medical journal, 310(6989), 1995, pp. 1225-1229

Abstract

Objective-To study the association between upper and lower respiratory viral infections and acute exacerbations of asthma in schoolchildrenin the community. Design-Community based 13 month longitudinal study using diary card respiratory symptom and peak expiratory flow monitoring to allow early sampling for viruses. Subjects-1O8 Children aged 9-11 years who had reported wheeze or cough, or both, in a questionnaire. Setting-Southampton and surrounding community. Main outcome measures-Upper and lower respiratory viral infections detected by polymerase chain reaction or conventional methods, reported exacerbations of asthma, computer identified episodes of respiratory tract symptoms or peak flow reductions. Results-Viruses were detected in 80% of reported episodes of reduced peak expiratory flow, 80% of reported episodes of wheeze, and in 85% of reported episodes of upper respiratory symptoms, cough, wheeze, and a fall in peak expiratory flow. The median duration of reported falls in peak expiratory flow was 14 days, and the median maximum fall in peak expiratory flow was 81 1/min. The most commonly identified virus type was rhinovirus. Conclusions-This study supports the hypothesis that upper respiratory viral infections are associated with80-85% of asthma exacerbations in school age children.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/08/20 alle ore 12:54:47