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Titolo:
IN-UTERO VIRILIZATION BY DANAZOL - EFFECTS ON ADRENAL STEROIDOGENESIS
Autore:
PICCO P; GARIBALDI LR; DIROCCO M; PODESTA E; FARACI M; LAVRATTO P; GATTORNO M; PANG S;
Indirizzi:
CARDINAL GLENNON CHILDRENS HOSP,DEPT PEDIAT,1465 S GRAND BLVD ST LOUIS MO 63104 GIANNINA GASLINI INST,DEPT PEDIAT 2 GENOA ITALY
Titolo Testata:
Adolescent and pediatric gynecology
fascicolo: 2, volume: 8, anno: 1995,
pagine: 97 - 100
SICI:
0932-8610(1995)8:2<97:IVBD-E>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Keywords:
FEMALE PSEUDOHERMAPHRODITISM; PRENATAL VIRILIZATION; DANAZOL; ANDROGENS; ADRENAL STEROIDOGENESIS;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
P. Picco et al., "IN-UTERO VIRILIZATION BY DANAZOL - EFFECTS ON ADRENAL STEROIDOGENESIS", Adolescent and pediatric gynecology, 8(2), 1995, pp. 97-100

Abstract

The measurement of serum concentrations of Delta 4- and Delta 5-steroid hormones after intravenous adrenocorticotropic hormone stimulation in a 4-month-old infant female pseudohermaphrodite, who had been exposed to danazol in the first 20 weeks of gestation, showed normal 17-hydroxyprogesterone and compound S (11-deoxycortisol) but elevated 17-hydroxypregnenolone. Thus, protracted postnatal inhibition of adrenal 3 beta-hydroxysteroid dehydrogenase activity may occur after in utero exposure to danazol.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 05:21:59