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Titolo:
FOLLICULAR-FLUID INSULIN-LIKE GROWTH-FACTOR-I AND INSULIN-LIKE GROWTHFACTOR-II CONCENTRATIONS VARY AS A FUNCTION OF DAY-3 SERUM FOLLICLE-STIMULATING-HORMONE
Autore:
SEIFER DB; GIUDICE LC; DSUPIN BA; HANING RV; FRISHMAN GN; BURGER HG;
Indirizzi:
BROWN UNIV,WOMEN & INFANTS HOSP,SCH MED,DEPT OBSTET & GYNECOL,DIV REPROD ENDOCRINOL PROVIDENCE RI 02905 STANFORD UNIV,MED CTR,DEPT GYNECOL & OBSTET STANFORD CA 94305 MONASH MED CTR,PRINCE HENRYS INST MED RES,DEPT OBSTET & GYNECOL CLAYTON VIC AUSTRALIA
Titolo Testata:
Human reproduction
fascicolo: 4, volume: 10, anno: 1995,
pagine: 804 - 806
SICI:
0268-1161(1995)10:4<804:FIGAIG>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN GRANULOSA-CELLS; DEOXYRIBONUCLEIC-ACID; CYCLE;
Keywords:
FOLLICULAR FLUID; GROWTH FACTORS; OVARIAN RESERVE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
D.B. Seifer et al., "FOLLICULAR-FLUID INSULIN-LIKE GROWTH-FACTOR-I AND INSULIN-LIKE GROWTHFACTOR-II CONCENTRATIONS VARY AS A FUNCTION OF DAY-3 SERUM FOLLICLE-STIMULATING-HORMONE", Human reproduction, 10(4), 1995, pp. 804-806

Abstract

We determined follicular fluid concentrations of insulinlike growth factor (IGF)-I, IGF-II and inhibin as a function of day 3 serum follicle stimulating hormone (FSH) in 16 women undergoing follicular fluid aspiration in preparation for in-vitro fertilization and embryo transfer, Follicular fluid concentrations of IGF-I and IGF-II were significantly less in the 'low' FSH group as compared to the 'high' FSH group. The mean IGF-I concentration was 67.6 ng/ml [confidence intervals (CI) 51.6-92.5] in the 'low' FSH group compared to 87.1 ng/ml (CI 72.8-104.2; P < 0.025) in the 'high' FSH group. Mean IGF-II concentrations were 354.8 ng/ml (CI 297.8-422.9) in the 'low' FSH group compared to 489.8 ng/ml (CI 384.6-624.5; P < 0.05) in the 'high' FSH group, Follicular fluid inhibin concentrations did not differ between groups. These differences in follicular fluid IGF as a function of day 3 FSH may raise questions regarding the role growth factors play in the physiological processes of the ageing follicle.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 08:05:24