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Titolo:
FAILURE OF PASSIVE TRANSFER IN FOALS - INCIDENCE AND OUTCOME ON 4 STUDS IN NEW-SOUTH-WALES
Autore:
TYLERMCGOWAN CM; HODGSON JL; HODGSON DR;
Indirizzi:
UNIV SYDNEY,RURAL VET CTR,PRIVATE MAILBAG 4,WEROMBI RD CAMDEN NSW 2570 AUSTRALIA
Titolo Testata:
Australian Veterinary Journal
fascicolo: 1, volume: 75, anno: 1997,
pagine: 56 - 59
SICI:
0005-0423(1997)75:1<56:FOPTIF>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPOGAMMAGLOBULINEMIA; DIAGNOSIS;
Keywords:
FAILURE OF PASSIVE TRANSFER; COLOSTRAL SPECIFIC GRAVITY; FOALS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
C.M. Tylermcgowan et al., "FAILURE OF PASSIVE TRANSFER IN FOALS - INCIDENCE AND OUTCOME ON 4 STUDS IN NEW-SOUTH-WALES", Australian Veterinary Journal, 75(1), 1997, pp. 56-59

Abstract

Objective To determine the regional incidence and effectiveness of treatment of failure of passive transfer (FPT) in foals. Design A study of disease incidence. Animals Eighty-eight foals and 57 mares from four studs in the practice area of the Rural Veterinary Centre were tested. Procedure Foals were tested for their serum IgG and total serum protein (TSP) concentration within the first 72 hours of life. Colostrum was collected from mares and specific gravity determined. FPT and partial failure of passive transfer (PFPT) of immunoglobulins was diagnosed when serum IgG concentrations were < 4 g/L and 4 to 8 g/L respectively. Owners of feats diagnosed with FPT were offered treatment with 1 to 2 L plasma (TSP > 70 g/L); 9 (64%) of the affected foals were treated. Results Fourteen foals (16%) had FPT whereas 15 (17%) had PFPT. There were significant differences between the mean TSP concentration in foals with FPT (42.6 +/- 4.2 g/L), PFPT (48.1 +/- 3.9 g/L) and those acquiring adequate passive immunity (58.9 +/- 5.5 g/L) (P < 0.01). Sixteen (29%) mares had pre-suck colostral specific gravity < 1.060 and 12(71%) feats raised by these mares had FPT or PFPT. The incidence of severe disease (categorised by a sepsis score > fl, positive culture ofbacteria from blood or disease requiring hospitalisation) in all foals in the first 2 months of life was 10%. However, none of the nine foals with FPT that received plasma experienced severe disease. In contrast, foals with PFPT had an increased susceptibility to severe disease (P < 0.001) when compared with normal foals. Conclusion Treatment of foals with FPT may reduce the subsequent incidence of severe disease. Pre-suck colostral specific gravity and foal TSP may be used to predictthe likelihood of FPT and PFPT. Even though the number of feats studied is small the results highlight the importance of optimal managementpractices in reducing the incidence of FPT and disease associated with this process.

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Documento generato il 03/04/20 alle ore 13:41:40