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Titolo:
NEUROANATOMY OF THE PAIN SYSTEM AND OF THE PATHWAYS THAT MODULATE PAIN
Autore:
WILLIS WD; WESTLUND KN;
Indirizzi:
UNIV TEXAS,MED BRANCH,DEPT ANAT & NEUROSCI,301 UNIV BLVD GALVESTON TX77555
Titolo Testata:
Journal of clinical neurophysiology
fascicolo: 1, volume: 14, anno: 1997,
pagine: 2 - 31
SICI:
0736-0258(1997)14:1<2:NOTPSA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMATE SPINOTHALAMIC TRACT; DORSAL HORN NEURONS; ANTERIOR PRETECTAL NUCLEUS; PHASEOLUS-VULGARIS-LEUKOAGGLUTININ; NOXIOUS THERMAL-STIMULATION; LATERAL CERVICAL NUCLEUS; EXCITATORY AMINO-ACIDS; SPINAL NOCICEPTIVE TRANSMISSION; MIDBRAIN PERIAQUEDUCTAL GRAY; PERIPHERAL-NERVE INJURY;
Keywords:
PAIN; PAIN MODULATION; SENSITIZATION; NOCICEPTIVE PATHWAYS; ANALGESIA SYSTEMS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
384
Recensione:
Indirizzi per estratti:
Citazione:
W.D. Willis e K.N. Westlund, "NEUROANATOMY OF THE PAIN SYSTEM AND OF THE PATHWAYS THAT MODULATE PAIN", Journal of clinical neurophysiology, 14(1), 1997, pp. 2-31

Abstract

We review many of the recent findings concerning mechanisms and pathways for pain and its modulation, emphasizing sensitization and the modulation of nociceptors and of dorsal horn nociceptive neurons. We describe the organization of several ascending nociceptive pathways, including the spinothalamic, spinomesencephalic, spinoreticular, spinolimbic, spinocervical, and postsynaptic dorsal column pathways in some detail and discuss nociceptive processing in the thalamus and cerebral cortex. Structures involved in the descending analgesia systems, including the periaqueductal gray, locus ceruleus, and parabrachial area, nucleus raphe magnus, reticular formation, anterior prerectal nucleus. thalamus and cerebral cortex, and several components of the limbic systemare described and the pathways and neurotransmitters utilized are mentioned. Finally, we speculate on possible fruitful lines of research that might lead to improvements in therapy for pain.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 21:21:19