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Titolo:
HUMAN ENTERIC INFECTION WITH ANCYLOSTOMA-CANINUM - HOOKWORMS REAPPRAISED IN THE LIGHT OF A NEW ZOONOSIS
Autore:
PROCIV P; CROESE J;
Indirizzi:
UNIV QUEENSLAND,DEPT PARASITOL BRISBANE QLD 4072 AUSTRALIA TOWNSVILLE GEN HOSP,DEPT GASTROENTEROL TOWNSVILLE QLD 4812 AUSTRALIA
Titolo Testata:
Acta Tropica
fascicolo: 1, volume: 62, anno: 1996,
pagine: 23 - 44
SICI:
0001-706X(1996)62:1<23:HEIWA->2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUTANEOUS LARVA MIGRANS; EOSINOPHILIC ENTERITIS; LACTATIONAL TRANSMISSION; PARASITIC NEMATODES; NECATOR-AMERICANUS; TISSUE INVASION; TOXOCARA-CANIS; DOG HOOKWORM; ANTICOAGULANT; INVITRO;
Keywords:
HOOKWORM; ZOONOSES; ANCYLOSTOMA CANINUM; EOSINOPHILIC ENTERITIS; IMMUNODIAGNOSIS; LARVA MIGRANS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
105
Recensione:
Indirizzi per estratti:
Citazione:
P. Prociv e J. Croese, "HUMAN ENTERIC INFECTION WITH ANCYLOSTOMA-CANINUM - HOOKWORMS REAPPRAISED IN THE LIGHT OF A NEW ZOONOSIS", Acta Tropica, 62(1), 1996, pp. 23-44

Abstract

Recent studies in northeastern Australia indicate that enteric infection with Ancylostoma caninum is a leading cause of human eosinophilic enteritis. Much more frequent accompaniments of this infection are obscure abdominal pain with or without blood eosinophilia, while a large part of the population is probably infected asymptomatically. These conclusions are based on extensive serological investigations in patients and control subjects, as well as 15 cases in which single, adult hookworms were identified in situ in patients. In no case has more than one worm been identified, and none has been fully mature, so the infections have never been patent. Aphthous ulcers of the terminal ileum, caecum and colon have been seen in association with this infection and have also been observed in almost 5% of patients who are colonoscoped in north Queensland. Serodiagnosis has relied on an IgG and IgE ELISA using excretory-secretory antigens from adult A. caninum, but Western blot using these antigens to identify IgG4 antibodies to a protein of molecular weight 68 kDa (Ac68) promises to be more specific and sensitive. However, identical antigens appear to be secreted by the anthropophilic hookworms as well. The clinical, public health and biological significance of these findings are discussed in detail.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 03:56:28