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Titolo:
REVIEW ARTICLE - ANTI-DIARRHEAL PHARMACOLOGY AND THERAPEUTICS
Autore:
SCHILLER LR;
Indirizzi:
BAYLOR UNIV,MED CTR,DEPT INTERNAL MED,GASTROINTESTINAL PHYSIOL LAB,3500 GASTON AVE DALLAS TX 75246 UNIV TEXAS,SW MED CTR,DEPT INTERNAL MED DALLAS TX 00000 BAYLOR UNIV,MED CTR,DEPT INTERNAL MED,GASTROINTESTINAL PHYSIOL LAB DALLAS TX 75246
Titolo Testata:
Alimentary pharmacology & therapeutics
fascicolo: 2, volume: 9, anno: 1995,
pagine: 87 - 106
SICI:
0269-2813(1995)9:2<87:RA-APA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACTING SOMATOSTATIN ANALOG; RABBIT ILEAL MUCOSA; INTESTINAL ELECTROLYTE TRANSPORT; IMMUNODEFICIENCY-SYNDROME AIDS; MALIGNANT CARCINOID-SYNDROME; PANCREATIC ENDOCRINE TUMORS; STIMULATED FLUID SECRETION; TOXIGENIC ESCHERICHIA-COLI; ZOLLINGER-ELLISON SYNDROME; MULTIPLE OPIATE RECEPTORS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
271
Recensione:
Indirizzi per estratti:
Citazione:
L.R. Schiller, "REVIEW ARTICLE - ANTI-DIARRHEAL PHARMACOLOGY AND THERAPEUTICS", Alimentary pharmacology & therapeutics, 9(2), 1995, pp. 87-106

Abstract

Anti-diarrhoeal drugs reduce the symptoms of diarrhoea (loose stool consistency, frequency of defecation and excessive stool weight) by effects on intestinal transit, mucosal transport or luminal contents, Opiates and opioids are the most useful antidiarrhoeal agents, Opiates have major effects on intestinal transit; pro-absorptive and anti-secretory effects are less well documented, but may be important for some ofthese drugs. Alpha-adrenergic agonists, somatostatin analogues and several other agents have had limited clinical use; these drugs may modify mucosal transport in addition to slowing transit. Adsorbents, bismuth and stool texture modifiers are used frequently by the public, but their efficacy is largely unproven. Oral rehydration solutions have had the greatest impact in saving lives and continue to be improved. Many new approaches to the treatment of diarrhoea are yet to be exploited.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:29:10