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Titolo:
EFFECTS OF EXPOSURE TO HYPOXIA ON THE SIGNAL-AVERAGED ELECTROCARDIOGRAM IN HEALTHY-SUBJECTS
Autore:
ROCHE F; BARTHELEMY JC; ADAMEC R; GEYSSANT A; LACOUR JR;
Indirizzi:
CHU NORD,NIVEAU 6 F-42055 ST ETIENNE 02 FRANCE UNIV HOSP ST ETIENNE ST ETIENNE FRANCE GIP EXERCISE,PHYSIOL LAB ST ETIENNE FRANCE UNIV HOSP GENEVA GENEVA SWITZERLAND UNIV HOSP LYON LYON FRANCE PHYSIOL LAB LYON FRANCE
Titolo Testata:
European heart journal
fascicolo: 4, volume: 16, anno: 1995,
pagine: 539 - 544
SICI:
0195-668X(1995)16:4<539:EOETHO>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONSUSTAINED VENTRICULAR-TACHYCARDIA; CORONARY-ARTERY DISEASE; BODY-SURFACE QRS; MYOCARDIAL-INFARCTION; LATE POTENTIALS; PROGNOSTIC-SIGNIFICANCE; QUANTITATIVE-ANALYSIS; EXERCISE; STIMULATION; VARIABLES;
Keywords:
SIGNAL-AVERAGED ELECTROCARDIOGRAM; NORMOBARIC HYPOXIA; VENTRICULAR LATE POTENTIALS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
F. Roche et al., "EFFECTS OF EXPOSURE TO HYPOXIA ON THE SIGNAL-AVERAGED ELECTROCARDIOGRAM IN HEALTHY-SUBJECTS", European heart journal, 16(4), 1995, pp. 539-544

Abstract

The effects of hypoxia on the signal-averaged ECG (SAECG) were investigated in 26 healthy active subjects with no suggestion of cardiac disease. The SAECG was recorded in each resting subject in normoxic and hypoxic normobaric conditions (inspired O-2 fraction 20.7 vs 10.0%) which lowered resting arterial O-2 saturation from 98.6 +/- 0.6% to 77.7 /- 8%. Recordings from four subjects (three men) met the definition of abnormal late potentials at baseline; in all these subjects but one,who exhibited an improved but still abnormal QRS duration, these parameters returned to normal in hypoxic conditions. The duration of the filtered QRS was significantly reduced (from 107.6 +/- 13.2 to 101.6 +/- 11.3 ms, P<0.01), the duration of the low amplitude signals in the terminal portion of the QRS <40 mu V (LAS) significantly decreased (from 26.5 +/- 9.5 to 22.7 +/- 7.9 ms, P<0.05) and the root mean square voltage in the last 40 ms (Term-RMS) increased non-significantly (from 55.8 +/- 40.2 to 69.1 +/- 38.3 mu V, P=0.058). Hypoxia determined a higher (P<0.05) heart rate increase in subjects with abnormal records than in normal subjects. These data could be related to a sympathic discharge They suggest that: (1) variation in heart rate could affect the SAECG; (2) exposure to hypoxia improves SAECG parameters in healthy subjects, possibly related to sympathetic discharge; (3) abnormal recordscollected during sinus bradycardia could represent a type of false-positive expression of late potentials in young active adults.

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Documento generato il 01/04/20 alle ore 02:17:25