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Titolo:
NONHEREDITARY COLONIC ANGIODYSPLASIAS - HISTOMORPHOMETRIC APPROACH TOTHEIR PATHOGENESIS
Autore:
NAVEAU S; LEGERRAVET MB; HOUDAYER C; BEDOSSA P; LEMAIGRE G; CHAPUT JC;
Indirizzi:
HOP ANTOINE BECLERE,DEPT GASTROENTEROL,157 RUE PORTE TRIVAUX F-92141 CLAMART FRANCE HOP ANTOINE BECLERE,DEPT PATHOL ANAT F-92141 CLAMART FRANCE HOP BICETRE,DEPT PATHOL ANAT F-94270 LE KREMLIN BICETR FRANCE
Titolo Testata:
Digestive diseases and sciences
fascicolo: 4, volume: 40, anno: 1995,
pagine: 839 - 842
SICI:
0163-2116(1995)40:4<839:NCA-HA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTROINTESTINAL ANGIODYSPLASIA; VONWILLEBRANDS DISEASE; AORTIC-STENOSIS; ASSOCIATION;
Keywords:
ANGIODYSPLASIAS; COLON; HISTOMORPHOMETRY; ALCOHOLIC CIRRHOSIS; PATHOGENESIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
S. Naveau et al., "NONHEREDITARY COLONIC ANGIODYSPLASIAS - HISTOMORPHOMETRIC APPROACH TOTHEIR PATHOGENESIS", Digestive diseases and sciences, 40(4), 1995, pp. 839-842

Abstract

The pathogenesis of colonic angiodysplasias, more accurately termed vascular ectasias (VE) has not been definitely established. The aim of this study was to assess that the VE of noncirrhotic patients are not associated with diffuse abnormalities of the colonic mucosal microvasculature unlike the VE of cirrhotic patients. Three groups of nine consecutive patients were studied: group I, control patients with an irritable bowel syndrome; group II, noncirrhotic patients with VE; and group III, alcoholic cirrhotics with VE. A histomorphometric analysis of normal-appearing colonic mucosa was achieved from biopsies taken at sixpredetermined sites. Noncirrhotics with VE had a significantly lower mean number of mucosal capillaries and a significantly lower mean cross-sectional area of mucosal capillaries than alcoholic cirrhotics withVE. Alcoholic cirrhotics with VE had a significant increase of all the vascular parameters compared to the control group. There was no difference between the control patients and the noncirrhotic patients withVE. These results suggest that the VE of noncirrhotic and cirrhotic patients are entities of distinct pathogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 19:51:53