Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EFFECTS OF EARLY REARING ENVIRONMENT ON IMMUNE-RESPONSES OF INFANT RHESUS-MONKEYS
Autore:
LUBACH GR; COE CL; ERSHLER WB;
Indirizzi:
UNIV WISCONSIN,WISCONSIN REG PRIMATE RES CTR,1223 CAPITOL COURT MADISON WI 53706 UNIV WISCONSIN,DEPT PSYCHOL MADISON WI 53706 UNIV WISCONSIN,DEPT MED MADISON WI 53706
Titolo Testata:
Brain, behavior, and immunity
fascicolo: 1, volume: 9, anno: 1995,
pagine: 31 - 46
SICI:
0889-1591(1995)9:1<31:EOEREO>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
KILLER-CELL-ACTIVITY; MATERNAL SEPARATION; ANTIBODY-RESPONSES; IMMUNOLOGICAL CONSEQUENCES; NONHUMAN-PRIMATES; BODY-TEMPERATURE; STRESS; DEPRESSION; DISEASE; PROLIFERATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
82
Recensione:
Indirizzi per estratti:
Citazione:
G.R. Lubach et al., "EFFECTS OF EARLY REARING ENVIRONMENT ON IMMUNE-RESPONSES OF INFANT RHESUS-MONKEYS", Brain, behavior, and immunity, 9(1), 1995, pp. 31-46

Abstract

In animals, perturbations of the rearing environment have been shown to alter behavior, cognition, and physiology, including immune responses. In order to evaluate the effect of early rearing conditions on thedevelopment of immune responses in the infant primate, several immunological measures were assessed in rhesus monkey infants, nursery-reared (NR) or mother-reared (MR), from birth to 2 years of age. Rearing inthe absence of the mother affected several aspects of cellular immunity. NR monkeys had significantly lower proportions of CD8 cells and lower natural killer cell activity than did MR monkeys. In contrast, their lymphocyte proliferation responses to mitogen stimulation were higher than those of MR monkeys. An attempt to behaviorally rehabilitate the NR infants at 1 year of age did not result in a recovery of normal immune responses. This study indicates that abnormal early rearing mayhave long-lasting effects on the immune system, which could have health consequences later in life. (C) 1995 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 00:57:36