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Titolo:
AGENESIS OF THE DUCTUS VENOSUS AND ITS CORRELATION TO HYDROPS-FETALISAND THE FETAL HEPATIC CIRCULATION - CASE-REPORTS AND REVIEW OF THE LITERATURE
Autore:
SIVEN M; LEY D; HAGERSTRAND I; SVENNINGSEN N;
Indirizzi:
UNIV LUND HOSP,DEPT PEDIAT PATHOL S-22185 LUND SWEDEN UNIV LUND HOSP,DEPT PEDIAT S-22185 LUND SWEDEN
Titolo Testata:
PEDIATRIC PATHOLOGY & LABORATORY MEDICINE
fascicolo: 1, volume: 15, anno: 1995,
pagine: 39 - 50
SICI:
1077-1042(1995)15:1<39:AOTDVA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD FLOWS; UMBILICAL VEIN; LIVER; LAMB;
Keywords:
DUCTUS VENOSUS; HYDROPS FETALIS; MALFORMATION; PORTAL HYPERTENSION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
M. Siven et al., "AGENESIS OF THE DUCTUS VENOSUS AND ITS CORRELATION TO HYDROPS-FETALISAND THE FETAL HEPATIC CIRCULATION - CASE-REPORTS AND REVIEW OF THE LITERATURE", PEDIATRIC PATHOLOGY & LABORATORY MEDICINE, 15(1), 1995, pp. 39-50

Abstract

Under normal conditions about 50% of the placental venous return bypasses the liver through the ductus venosus. This blood flow is preferentially directed toward the foramen ovale and provides optimum oxygenation to the fetal heart and brain. Absence of the ductus venosus is a rare vascular anomaly, the significance of which has been disputed. We distinguish the pattern in which the liver is entirely bypassed, a manifestation of a fundamental malformation in the umbilical venous system, from the pattern in which the ductus venosus is absent despite a normal course of the umbilical vein. We review the literature regarding the latter and report eight new cases. Three of the four previously reported cases showed associated malformations and two of them suffered from portal congestion and hydrops. Among our eight cases three showedsevere malformations in the cardiovascular system. Three cases presented themselves with hydrops fetalis and disturbance in the portal circulation, and two cases expressed signs of intrauterine asphyxia. The absence of the ductus venosus might be a minor vascular maldevelopment resulting in an early disturbance in the portal circulation. Our findings suggest that this anomaly might induce hydrops fetalis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 15:27:21