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Titolo:
NOC, A NITRIC-OXIDE-RELEASING COMPOUND, INDUCES DOSE-DEPENDENT APOPTOSIS IN MACROPHAGES
Autore:
SHIMAOKA M; IIDA T; OHARA A; TAENAKA N; MASHIMO T; HONDA T; YOSHIYA I;
Indirizzi:
OSAKA UNIV,MICROBIAL DIS RES INST SUITA OSAKA 565 JAPAN OSAKA UNIV HOSP,INTENS CARE UNIT SUITA OSAKA 565 JAPAN OSAKA UNIV,SCH MED,DEPT ANESTHESIOL SUITA OSAKA 565 JAPAN
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 2, volume: 209, anno: 1995,
pagine: 519 - 526
SICI:
0006-291X(1995)209:2<519:NANCID>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
THYMOCYTE APOPTOSIS; PROGRAMMED DEATH; CELLS; PRODUCT; INVITRO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
M. Shimaoka et al., "NOC, A NITRIC-OXIDE-RELEASING COMPOUND, INDUCES DOSE-DEPENDENT APOPTOSIS IN MACROPHAGES", Biochemical and biophysical research communications, 209(2), 1995, pp. 519-526

Abstract

The ability of exogenous nitric oxide (NO) to induce apoptosis in macrophages was analyzed using NOC, a NO-releasing compound, as a source of NO. Exogenous NO was shown to induce apoptosis in a dose dependent manner. Quantitative analysis revealed that the amount of NO required to induce apoptosis in more than half of macrophages exposed was 100 times larger than that for endogenous NO-induced apoptosis. NOC proved to be a convenient and useful tool for investigation of apoptosis related to NO. (C) 1995 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:54:32