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Titolo:
VARIABILITY IN DISTRIBUTION AND POPULATIONS OF GAP-JUNCTIONS IN FERRET TRACHEA DURING POSTNATAL-DEVELOPMENT
Autore:
CARSON JL; COLLIER AM; HU SCS; MCLACHLAN JB;
Indirizzi:
UNIV N CAROLINA,FRANK PORTER GRAHAM CHILD DEV CTR,DEPT PEDIAT,CB 7220CHAPEL HILL NC 27599 UNIV N CAROLINA,FRANK PORTER GRAHAM CHILD DEV CTR,DEPT CELL BIOL & ANAT CHAPEL HILL NC 27599 UNIV N CAROLINA,CTR ENVIRONM MED & LUNG BIOL CHAPEL HILL NC 27599
Titolo Testata:
American journal of physiology. Lung cellular and molecular physiology
fascicolo: 4, volume: 12, anno: 1995,
pagine: 576 - 583
SICI:
1040-0605(1995)12:4<576:VIDAPO>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTER-CELLULAR COMMUNICATION; RAT-LIVER; INTERCELLULAR-JUNCTIONS; REGENERATING LIVER; GUINEA-PIGS; PROTEIN; EPITHELIUM; CLONING;
Keywords:
AIRWAY EPITHELIUM; INTERCELLULAR COMMUNICATION; IMMUNOCYTOCHEMISTRY; MICROSCOPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J.L. Carson et al., "VARIABILITY IN DISTRIBUTION AND POPULATIONS OF GAP-JUNCTIONS IN FERRET TRACHEA DURING POSTNATAL-DEVELOPMENT", American journal of physiology. Lung cellular and molecular physiology, 12(4), 1995, pp. 576-583

Abstract

Immunocytochemical probes have been used to characterize gap junctiondistribution in the postnatal ferret trachea by epifluorescence and by laser scanning confocal and electron microscopy. A battery of antibodies directed against fragments of different connexins localized beta(1)- and beta(2)-gap junction antigens (connexins 32 and 26, respectively) at the intercellular borders of the superficial epithelium while alpha(1)-gap junction antigen (connexin 43) was localized to the loose connective tissues. Gap junction labeling in the superficial epithelium declined in the first weeks of life but persisted in the developing submucosal glands to the weanling stage. Localization of the alpha- and beta-antigens was specific for connective tissues and epithelial layers, respectively. These observations suggest that communication competence is an important component of early development in the mammalian airways.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 16:16:10