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Titolo:
THE EMERGENCE OF FREE-RADICALS AFTER ACOUSTIC TRAUMA AND STRIAL BLOOD-FLOW
Autore:
YAMANE H; NAKAI Y; TAKAYAMA M; KONISHI K; IGUCHI H; NAKAGAWA T; SHIBATA S; KATO A; SUNAMI K; KAWAKATSU C;
Indirizzi:
OSAKA CITY UNIV,SCH MED,DEPT OTOLARYNGOL,ABENO KU,1-5-7 ASAHIMACHI OSAKA 545 JAPAN
Titolo Testata:
Acta oto-laryngologica
, , anno: 1995, supplemento:, 519
pagine: 87 - 92
SICI:
0001-6489(1995):<87:TEOFAA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISCHEMIA;
Keywords:
NOISE INJURY; COCHLEAR BLOOD FLOW; SUPEROXIDE; RECIRCULATION INJURY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
H. Yamane et al., "THE EMERGENCE OF FREE-RADICALS AFTER ACOUSTIC TRAUMA AND STRIAL BLOOD-FLOW", Acta oto-laryngologica, 1995, pp. 87-92

Abstract

The effect of acoustic trauma on cochlear strial circulation was investigated immunohistologically in the guinea pig. Kanamycin was used asa tracer of blood flow. Moreover, histochemical examinations were made to reveal the emergence of free radicals in the cochlea following acoustic trauma. At 5 min (5 min after intense sound exposure 120-125 dBSPL, 3 h) the blood flow in the stria vascularis was greatly diminished. At 2 h the strial blood Row started to recirculate and at 6 h it appeared to have returned to normal. Superoxide anion radicals (O-2(-))emerged along the luminal membrane of the marginal cells of the striavascularis at 5 min. O-2(-) disappeared at 30 min, but reappeared at 2 h. The cause of its emergence at 5 min was obscure. However, the strange phenemenon that O-2(-) emerged again at 2 h seemed ascribable to the re-circulation of strial blood flow after sound exposure.

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Documento generato il 02/12/20 alle ore 08:14:26