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Titolo:
DIETARY FATTY-ACIDS MODULATE HOST BACTERIOCIDAL RESPONSE, MICROBIAL TRANSLOCATION AND SURVIVAL FOLLOWING BLOOD-TRANSFUSION AND THERMAL-INJURY
Autore:
GIANOTTI L; ALEXANDER JW; EAVESPYLES T; FUKUSHIMA R;
Indirizzi:
UNIV CINCINNATI,COLL MED,DEPT SURG,DIV TRANSPLANTAT,231 BETHESDA AVE CINCINNATI OH 45267 UNIV CINCINNATI,COLL MED,DEPT SURG,DIV TRANSPLANTAT CINCINNATI OH 45267
Titolo Testata:
Clinical nutrition
fascicolo: 6, volume: 15, anno: 1996,
pagine: 291 - 296
SICI:
0261-5614(1996)15:6<291:DFMHBR>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
BACTERIAL TRANSLOCATION; BURN INJURY; FISH-OIL; INTESTINAL BACTERIA; ENTERAL NUTRITION; GUINEA-PIGS; MACROPHAGE; METABOLISM; INFECTION; INFLAMMATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
L. Gianotti et al., "DIETARY FATTY-ACIDS MODULATE HOST BACTERIOCIDAL RESPONSE, MICROBIAL TRANSLOCATION AND SURVIVAL FOLLOWING BLOOD-TRANSFUSION AND THERMAL-INJURY", Clinical nutrition, 15(6), 1996, pp. 291-296

Abstract

The effect of dietary lipids on bacterial translocation, killing of translocated organisms and host survival was studied in a burned animalmodel. Balb/c mice were fed with one of the three experimental AlN-76A diets (containing 15% of energy from fish oil, safflower oil or a 50:50 mixture), AlN-76A without added lipids or a nonpurified stock diet. All animals were transfused on day 10. On day 15, the animals were gavaged with 10(10) C-14 radiolabelled Escherichia coli and given a 20%burn injury. Survival was 84% in the fish oil group versus 36% in thesafflower oil and 50:50 diet groups, and 25% and 20% in the two control groups (P < 0.0001). The numbers of viable translocating bacteria were reduced in all tested organs in the fish oil groups compared to the other groups. It is concluded that a diet enriched in fish oil has beneficial effects during gut-derived sepsis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 18:33:14