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Titolo:
ENDARTERECTOMY FOR ASYMPTOMATIC CAROTID-A RTERY STENOSIS - RESULTS OFTHE ACAS-STUDY
Autore:
MAST H; CHAMBLESS LE; MOHR JP; TOOLE JF;
Indirizzi:
FREE UNIV BERLIN,KLINIKUM BENJAMIN FRANKLIN,NEUROL KLIN,NEUROVASKULARE ENIHEIT,HINDENBURGDAMM 30 D-12200 BERLIN GERMANY
Titolo Testata:
Zentralblatt fur Chirurgie
fascicolo: 12, volume: 121, anno: 1996,
pagine: 1033 - 1035
SICI:
0044-409X(1996)121:12<1033:EFACRS>2.0.ZU;2-G
Fonte:
ISI
Lingua:
GER
Keywords:
ENDARTERECTOMY; THROMBOENDARTERECTOMY; SYMPTOMATIC CAROTID ARTERY STENOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
5
Recensione:
Indirizzi per estratti:
Citazione:
H. Mast et al., "ENDARTERECTOMY FOR ASYMPTOMATIC CAROTID-A RTERY STENOSIS - RESULTS OFTHE ACAS-STUDY", Zentralblatt fur Chirurgie, 121(12), 1996, pp. 1033-1035

Abstract

Objective: To determine the effect of endarterectomy on the primary prevention of ischemic stroke in patients with asymptomatic carotid artery stenosis. Methods: In a prospective, randomized, multicenter trial1659 patients with asymptomatic carotid stenosis of 60 % or more werestudied in two treatment arms (endarterectomy: n=825; medical therapy: n=834). Endpoints were: (1) ischemic stroke in the vascular territory of the study artery, (2) any perioperative stroke or any perioperative death. Results: The Kaplan-Meier 5-year-risk estimation showed a relative risk reduction of 53% (confidence interval: 22 %-72 %) for patients in the surgical arm. The combined perioperative morbidity and mortality rate was 2.3 %. Conclusion: Endarterectomy of asymptomatic carotid artery stenosis performed with a perioperative complication rate of less than 3% reduces the 5-year risk of ipsilateral stroke.

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Documento generato il 25/11/20 alle ore 07:25:08