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Titolo:
REQUIREMENTS FOR CONTROLLED CLINICAL-TRIALS OF PREOPERATIVE CARDIOVASCULAR RISK REDUCTION
Autore:
COHEN MC; MCKENNA C; LEWIS SM; MULLER JE;
Indirizzi:
HARVARD UNIV,NEW ENGLAND DEACONESS HOSP,SCH MED,INST PREVENT CARDIOVASC DIS,DIV CARDIOVASC BOSTON MA 02215
Titolo Testata:
Controlled clinical trials
fascicolo: 2, volume: 16, anno: 1995,
pagine: 89 - 95
SICI:
0197-2456(1995)16:2<89:RFCCOP>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERIPHERAL VASCULAR-SURGERY; MAJOR CARDIAC EVENTS; DISEASE;
Keywords:
PREOPERATIVE RISK ASSESSMENT; PREOPERATIVE CARDIAC TESTING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
M.C. Cohen et al., "REQUIREMENTS FOR CONTROLLED CLINICAL-TRIALS OF PREOPERATIVE CARDIOVASCULAR RISK REDUCTION", Controlled clinical trials, 16(2), 1995, pp. 89-95

Abstract

Although controlled clinical trials have had a major impact in many areas of cardiovascular disease management, they have had little influence on preoperative cardiac risk reduction. Over the past 2 years, we have conducted the Reduction of Cardiac Operative Risk (RCOR) Trial, apilot study designed to determine enrollment and event rates fora definitive trial evaluating a strategy to reduce cardiac risk associated with noncardiac surgery. This experience indicates that a successful, definitive trial will require recognition of the multiple questions tobe answered, accurate identification of the study population, a largesample size, cooperation between internists, surgeons, and anesthesiologists, and strategies to minimize cost. The high costs and difficulties of such a trial are likely to be outweighed by the enormous benefit of identifying the propel strategy for the use of the expensive testing methods that are currently employed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 20:03:05