Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ANALGESIC EFFECT OF 2 CALCITONINS AND IN-VITRO INTERACTION WITH OPIOIDS
Autore:
MARTIN MI; GOICOECHEA C; ORMAZABAL MJ; LOPEZ F; ALFARO MJ;
Indirizzi:
UNIV COMPLUTENSE MADRID,FAC MED,DEPT FARMACOL E-28040 MADRID SPAIN
Titolo Testata:
General pharmacology
fascicolo: 3, volume: 26, anno: 1995,
pagine: 641 - 647
SICI:
0306-3623(1995)26:3<641:AEO2CA>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINDING-SITE DISTRIBUTION; KAPPA-RECEPTOR AGONISTS; RABBIT VAS-DEFERENS; SALMON-CALCITONIN; ADENYLATE-CYCLASE; OPIATE RECEPTORS; MU-OPIATE; BRAIN; INVOLVEMENT; ANALOGS;
Keywords:
CALCITONIN; TAIL FLICK TEST; WRITHING TEST; OPIOID SYSTEM; VAS DEFERENS; GUINEA-PIG ILEUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M.I. Martin et al., "ANALGESIC EFFECT OF 2 CALCITONINS AND IN-VITRO INTERACTION WITH OPIOIDS", General pharmacology, 26(3), 1995, pp. 641-647

Abstract

1. When the analgesic effect of salmon-calcitonin (S-CT) and of eel-calcitonin (E-CT), as well as their influence on the morphine-analgesiawere compared, no significant differences were found. 2. While on isolated tissues, E-CT induced a significant increase on the effect of bremazocine, [D-Pen(2),D-Pen(5)]enkephalin and [Met(5)]enkephalin and nochanges were observed on the effect of DAMGO, suggesting that E-CT increases the effects of opioids acting on delta or kappa receptors but not on mu receptors. 3. These findings corroborate the possibility of interactions between calcitonin and the opioid system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 07:46:20