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Titolo:
AN IMMUNOHISTOCHEMICAL STUDY OF THE INCIDENCE AND SIGNIFICANCE OF CARCINOEMBRYONIC ANTIGEN IN MALIGNANT ENDOMETRIUM
Autore:
SIVRIDIS E; BUCKLEY CH; FOX H;
Indirizzi:
DEMOCRITUS UNIV THRACE,DEPT PATHOL ALEXANDROUPOLIS GREECE UNIV MANCHESTER,DEPT PATHOL SCI MANCHESTER LANCS ENGLAND ST MARYS HOSP,DEPT REPROD PATHOL MANCHESTER LANCS ENGLAND
Titolo Testata:
International journal of gynecological cancer
fascicolo: 3, volume: 5, anno: 1995,
pagine: 204 - 210
SICI:
1048-891X(1995)5:3<204:AISOTI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER; ADENOCARCINOMA; CARCINOMA; TISSUE; IMMUNOPEROXIDASE; LOCALIZATION; SPECIMENS; PLASMA; TUMORS;
Keywords:
CARCINOEMBRYONIC ANTIGEN; CARCINOMA; ENDOMETRIUM; IMMUNOCYTOCHEMISTRY; PROGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
E. Sivridis et al., "AN IMMUNOHISTOCHEMICAL STUDY OF THE INCIDENCE AND SIGNIFICANCE OF CARCINOEMBRYONIC ANTIGEN IN MALIGNANT ENDOMETRIUM", International journal of gynecological cancer, 5(3), 1995, pp. 204-210

Abstract

In an immunohistochemical study of the presence of carcinoembryonic antigen (CEA) in endometrial carcinomas, it was found that CEA was detectable in 92 of 171 neoplasms, an incidence of 53.8%. The antigen was unrelated to important prognostic variables, both clinical and histopathologic, and overall there was no difference in survival rates between CEA-positive and CEA-negative endometrial neoplasms during the 10-year follow-up period. CEA-negative carcinomas did, however, confer longer survival in certain subgroups of patients: those with adenocarcinomas arising from a hyperplastic endometrium, those with neoplasms of poor differentiation, and those who, in addition to surgery, received irradiation treatment. It is suggested that immunoperoxidase staining for CEA may provide an independent method for predicting radiosensitivity in endometrial carcinomas, and also may be indicative of prognosis within some forms of this malignancy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 20:34:01