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Titolo:
RELATIONSHIP BETWEEN HABITUAL PHYSICAL-ACTIVITY AND INSULIN AREA AMONG INDIVIDUALS WITH IMPAIRED GLUCOSE-TOLERANCE - THE SAN-LUIS VALLEY DIABETES STUDY
Autore:
REGENSTEINER JG; SHETTERLY SM; MAYER EJ; ECKEL RH; HASKELL WL; BAXTER J; HAMMAN RF;
Indirizzi:
UNIV COLORADO,SCH MED,DEPT PREVENT MED & BIOMETR,VASC MED SECT,BOX B-180,4200 E 9TH AVE DENVER CO 80262 UNIV COLORADO,SCH MED,DIV ENDOCRINOL DENVER CO 00000 KAISER PERMANENTE OAKLAND CA 00000 STANFORD UNIV,CTR RES DIS PREVENT STANFORD CA 94305
Titolo Testata:
Diabetes care
fascicolo: 4, volume: 18, anno: 1995,
pagine: 490 - 497
SICI:
0149-5992(1995)18:4<490:RBHPAI>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE-AGED MEN; RISK-FACTORS; ORAL GLUCOSE; EXERCISE; POPULATION; MELLITUS; SENSITIVITY; DISEASE; NIDDM; ASSOCIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
56
Recensione:
Indirizzi per estratti:
Citazione:
J.G. Regensteiner et al., "RELATIONSHIP BETWEEN HABITUAL PHYSICAL-ACTIVITY AND INSULIN AREA AMONG INDIVIDUALS WITH IMPAIRED GLUCOSE-TOLERANCE - THE SAN-LUIS VALLEY DIABETES STUDY", Diabetes care, 18(4), 1995, pp. 490-497

Abstract

OBJECTIVE-To determine whether higher levels of physical activity areassociated with lower fasting insulin levels and lower insulin areas under the oral glucose tolerance curve in individuals with impaired glucose tolerance (IGT) in a community setting. RESEARCH DESIGN AND METHODS-Data from a cross-sectional study of a population consisting of 219 Hispanic and non-Hispanic white men and women with IGT (by World Health Organization criteria) in two rural Colorado counties were analyzed. Total physical activity was assessed by a 7-day physical activity recall, from which metabolic equivalents (METs) were estimated (expressed as MET h/week). Relationships of MET h/week with fasting insulin levels and insulin areas were assessed while considering obesity, age, and other risk factors known to influence lasting insulin level and insulin area. RESULTS-Among all subjects, univariate analyses showed thathigher physical activity levels were associated with lower mean insulin areas and fasting insulin levels (both P less than or equal to 0.05). Multiple linear regression showed that higher levels of physical activity were significantly associated with lower values of the insulin area (P < 0.001) but not with fasting insulin levels. The relationshipbetween insulin area and habitual physical activity was independent of obesity, fat distribution, and age. CONCLUSIONS-On the basis of cross-sectional data, we conclude that higher levels of habitual physical activity are associated with lower insulin areas in a population of individuals individuals with IGT. Understanding the impact of physical activity on markers of insulin action in individuals with IGT is important because of the greatly enhanced risk of non-insulin-dependent diabetes mellitus and, hence, cardiovascular disease in this population.

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Documento generato il 24/11/20 alle ore 13:16:10