Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DL-3-I-123-IODO-ALPHA-METHYLTYROSINE UPTA KE IN BRAIN-TUMOR RECURRENCES
Autore:
GUTHTOUGELIDIS B; MULLER S; MEHDORN MM; KNUST EJ; DUTSCHKA K; REINERS C;
Indirizzi:
UNIV ESSEN GESAMTHSCH KLINIKUM,NUKL MED KLIN & POLIKLIN,HUFELANDSTR 55 D-45122 ESSEN GERMANY UNIV ESSEN GESAMTHSCH KLINIKUM,NUKL MED KLIN & POLIKLIN D-45122 ESSENGERMANY CHRISTIAN ALBRECHTS UNIV KIEL,NEUROCHIRURG KLIN KIEL GERMANY
Titolo Testata:
Nuklearmedizin
fascicolo: 2, volume: 34, anno: 1995,
pagine: 71 - 75
Fonte:
ISI
Lingua:
GER
Soggetto:
POSITRON EMISSION TOMOGRAPHY; AMINO-ACIDS; L-3-)I-123>IODO-ALPHA-METHYL TYROSINE; COMPUTED-TOMOGRAPHY; PET; METHIONINE; MELANOMA; MR; METHYLTYROSINE; ACCUMULATION;
Keywords:
BRAIN TUMORS; SPECT; IODO-ALPHA-METHYLTYROSINE (I-123-IMT);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
B. Guthtougelidis et al., "DL-3-I-123-IODO-ALPHA-METHYLTYROSINE UPTA KE IN BRAIN-TUMOR RECURRENCES", Nuklearmedizin, 34(2), 1995, pp. 71-75

Abstract

DL-3-I-123-iodo-alpha-methyltyrosine (I-123-IMT) is a radiopharmacon which concentrates in brain tumors and can be employed in SPECT. We performed 20 studies in 16 patients after neurosurgery for malignant brain tumors (localization of the primary tumor by CT/MRI). Tumor/non-tumor ratios (T/NT) were calculated in ROI-technique. In 17 cases there was a recurrence or tumor remnant. 14/17 were detectable by increased uptake (T/NT 1.43-2.25). The scans were correlated with CT/MRI studies and validated by biopsy (6/14) or follow-up. All 3 patients without recurrence (neuroradiological follow-up over 6-24 months) had a negativescan. I-123-IMT scintigraphy provides complementary information to CTand MRI. In equivocal neuroradiological or clinical cases it may be valuable in the detection of tumor recurrences and allows an earlier onset of therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 05:43:12