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Titolo:
SYMPATHETIC NERVOUS-SYSTEM ACTIVITY, BODY FATNESS, AND BODY-FAT DISTRIBUTION IN YOUNGER AND OLDER MALES
Autore:
POEHLMAN ET; GARDNER AW; GORAN MI; ARCIERO PJ; TOTH MJ; ADES PA; CALLESESCANDON J;
Indirizzi:
UNIV MARYLAND,CTR GERIATR RES EDUC & CLIN,BALTIMORE VET AFFAIRS MED CTR,DEPT MED,DIV GERONTOL BALTIMORE MD 21201 UNIV VERMONT,DEPT MED BURLINGTON VT 05405
Titolo Testata:
Journal of applied physiology
fascicolo: 3, volume: 78, anno: 1995,
pagine: 802 - 806
SICI:
8750-7587(1995)78:3<802:SNABFA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA NOREPINEPHRINE KINETICS; CATECHOLAMINE EXCRETION; APPEARANCE RATE; METABOLIC-RATE; ELDERLY MEN; AGE; OBESITY; HUMANS; NORADRENALINE; CLEARANCE;
Keywords:
NOREPINEPHRINE KINETICS; AGING; ADIPOSITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
E.T. Poehlman et al., "SYMPATHETIC NERVOUS-SYSTEM ACTIVITY, BODY FATNESS, AND BODY-FAT DISTRIBUTION IN YOUNGER AND OLDER MALES", Journal of applied physiology, 78(3), 1995, pp. 802-806

Abstract

It was hypothesized that an increase in total and central body fatness is related to higher sympathetic nervous system activity (SNSA) in older men. Resting SNSA was measured from norepinephrine (NE) kinetics in 69 younger (18-36 yr) and 69 healthy older men (55-80 yr). Body fatdistribution was estimated from the waist circumference, body composition from underwater weighing, peak oxygen consumption from a treadmill test to exhaustion, and dietary intake from food diaries. Plasma NE concentrations were 41% higher (P < 0.001) in older men due to a 27% increase (P < 0.001) in NE appearance rate and a tendency for a lower NE clearance rate (P = 0.08). NE appearance rate was higher in individuals of both age groups who exhibited a greater waist circumference andbody fatness (range of r values 0.49-0.69; P < 0.01). The waist circumference, and not-age, was the strongest predictor of the increase in NE appearance rate in older men. Statistically controlling for the waist circumference or body fatness diminished age-related differences inNE concentrations and in NE appearance rate. These findings suggest that an accumulation of total and central body fat is associated with higher levels of SNSA in older males.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 18:43:22