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Titolo:
KETOROLAC VERSUS MEPERIDINE-PLUS-PROMETHAZINE TREATMENT OF MIGRAINE HEADACHE - EVALUATIONS BY PATIENTS
Autore:
DAVIS CP; TORRE PR; WILLIAMS C; GRAY C; BARRETT K; KRUCKE G; PEAKE D; BASS B;
Indirizzi:
UNIV TEXAS,MED BRANCH,DEPT SURG,EMERGENCY SERV,J-73 GALVESTON TX 77555
Titolo Testata:
The American journal of emergency medicine
fascicolo: 2, volume: 13, anno: 1995,
pagine: 146 - 150
SICI:
0735-6757(1995)13:2<146:KVMTOM>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Keywords:
MIGRAINE HEADACHE; PATIENT EVALUATION; NAUSEA; KETOROLAC; MEPERIDINE; PROMETHAZINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
C.P. Davis et al., "KETOROLAC VERSUS MEPERIDINE-PLUS-PROMETHAZINE TREATMENT OF MIGRAINE HEADACHE - EVALUATIONS BY PATIENTS", The American journal of emergency medicine, 13(2), 1995, pp. 146-150

Abstract

This study was designed to compare and contrast the speed and efficacy of meperidine (75 mg)/promethazine (25 mg) intramuscularly to ketorolac (60 mg) intramuscularly, in a double-blind study in reducing the symptoms of migraine headache. Forty-two patients who presented to the emergency department between July 1992 and February 1993, with previous diagnoses of migraine headache, were considered for this study, Patients subjectively evaluated parameters of their migraine headaches (eg, pain and nausea) using a numeric scale and were later asked to reevaluate these same parameters at 30, 60, and 360 minutes after a single intramuscular injection of either ketorolac (60 mg) or meperidine (75 mg)/promethazine (25 mg). Sixty-eight percent of patients given meperidine/promethazine responded whereas 55% of patients given ketorolac responded. The responder group showed a statistically significant reduction in headache within 30 minutes with both drug regimens. There was no statistically significant difference between the number of responders in either group. The responders from both groups had relief that lasted 6 hours after injection, In the nonresponder groups, most of the patients withdrew within 1 hour after treatment, As determined by patient response to treatment of their migraine headaches, there was no statistically significant difference between the ketorolac and the meperidinel promethazine groups. Copyright (C) 1995 by W.B. Saunders Company

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/08/20 alle ore 00:30:30