Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DIURNAL NEUROENDOCRINE AND AUTONOMIC FUNCTION IN ACUTE AND REMITTED DEPRESSED MALE-PATIENTS
Autore:
TRESTMAN RL; YEHUDA R; COCCARO E; HORVATH T; KNOTT P; GABRIEL S; SIEVER LJ;
Indirizzi:
VET ADM MED CTR,PSYCHIAT SERV,116A,130 W KINGSBRIDGE RD BRONX NY 10468 CUNY MT SINAI SCH MED NEW YORK NY 10029 MED COLL PENN PHILADELPHIA PA 19129 NORTHPORT VET AFFAIRS MED CTR NORTHPORT NY 00000
Titolo Testata:
Biological psychiatry
fascicolo: 7, volume: 37, anno: 1995,
pagine: 448 - 456
SICI:
0006-3223(1995)37:7<448:DNAAFI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEXAMETHASONE SUPPRESSION TEST; ENDOGENOUS-DEPRESSION; CORTISOL SECRETION; PLASMA-LEVELS; NORADRENERGIC RESPONSES; AFFECTIVE-DISORDERS; GROWTH-HORMONE; PHASE-ADVANCE; 3-METHOXY-4-HYDROXYPHENYLGLYCOL; CLONIDINE;
Keywords:
DIURNAL; DEPRESSION; REMISSION; MHPG; CORTISOL; AUTONOMIC;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
R.L. Trestman et al., "DIURNAL NEUROENDOCRINE AND AUTONOMIC FUNCTION IN ACUTE AND REMITTED DEPRESSED MALE-PATIENTS", Biological psychiatry, 37(7), 1995, pp. 448-456

Abstract

This study evaluated diurnal data gathered hourly (1000 to 1800 hours) in males during acute depression and during remission of depression and in age-range/gender-matched normal controls. Mean, peak, variability, and time-course of the noradrenergic metabolite, plasma 3-methoxy,4-hydroxphenylglycol [MHPG]), plasma cortisol, and autonomic (mean arterial blood pressure [MAP] and heart rate) variables were examined. Compared to controls, acutely depressed but not remitted depressed patients had 1) an earlier plasma MHPG peak 2) a greater intragroup variability of plasma MHPG, 3) a higher plasma cortisol concentration, 4) a lower MAP, and 5) tended to increase MAP more slowly than did the normal controls, The time course of diurnal heart rate also differed in acutely depressed patients from controls: acutely depressed patients started higher and converged by midday to normal levels. These diurnal data lend limited support to the dysregulation hypotheses of depression that suggest normal circadian rhythmicities are altered or disrupted in acute depression and that peripheral manifestations of central dysregulation normalize in remission of depression.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 20:32:28