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Titolo:
PREVALENCE OF HUMAN PAPILLOMAVIRUS AMONG STD CLINIC ATTENDERS IN JAMAICA - ASSOCIATION OF YOUNGER AGE AND INCREASED SEXUAL-ACTIVITY
Autore:
FIGUEROA JP; WARD E; LUTHI TE; VERMUND SH; BRATHWAITE AR; BURK RD;
Indirizzi:
MINIST HLTH,EPIDEMIOL UNIT,30-34 HALF WAY TREE RD KINGSTON 5 JAMAICA ALBERT EINSTEIN COLL MED,DEPT PEDIAT BRONX NY 10467 ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL BRONX NY 10467 ALBERT EINSTEIN COLL MED,DEPT OBSTET & GYNECOL BRONX NY 10467 NIAID,DIV AIDS BETHESDA MD 20892
Titolo Testata:
Sexually transmitted diseases
fascicolo: 2, volume: 22, anno: 1995,
pagine: 114 - 118
SICI:
0148-5717(1995)22:2<114:POHPAS>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
CERVICAL NEOPLASIA; INFECTION; WOMEN; ADOLESCENTS; CANCER; POPULATION; KINGSTON; ANDREW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Figueroa et al., "PREVALENCE OF HUMAN PAPILLOMAVIRUS AMONG STD CLINIC ATTENDERS IN JAMAICA - ASSOCIATION OF YOUNGER AGE AND INCREASED SEXUAL-ACTIVITY", Sexually transmitted diseases, 22(2), 1995, pp. 114-118

Abstract

Background and Objectives: Human papillomavirus is the major etiologic agent of cervical cancer. Although the incidence of cancer of the cervix is high in Jamaica, the prevalence of human papillomavirus among Jamaican women has not been defined. Goal of the Study: To estimate the prevalence of human papillomavirus infection and associated risk factors in women attending an STD clinic in Kingston, Jamaica. Study Design: A cross-sectional survey was done of 202 women attending an STD clinic in Kingston in 1990. Cervical and vaginal cells were collected bylavage, and human papillomavirus genomes were detected in extracted DNA using low-stringency Southern blot hybridization. Results: Fifty-eight (28.7%) women were identified as HPV positive. Prevalence of HPV by age group was 39% in women 15-19 years old, 33% of women 20-24 yearsold, 31% in women 25-29 years old, and 17% in those 30 years or older. Increasing age was significantly associated with a lower prevalence of human papillomavirus infection (test for trend, P = 0.025). The effect of age was independent of years of sexual activity. Women reporting more than one sexual partner per month on average were found to havea significantly higher HPV prevalence (odds ratio 2.87, 95% confidence Interval 1.29-6.38), as were women who reported more frequent sex (test for trend, P = 0.006). Conclusions: Sexual behavior is associated with risk of human papillomavirus infection. The decrease of human papillomavirus prevalence in older women agrees with other studies that argue in favor of a biological effect, such as increased immunity to human papillomavirus with age. A better understanding of why immunity tohuman papillomavirus may develop in older women may provide the basisfor developing an effective vaccine to prevent cancer of the cervix.

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Documento generato il 28/01/21 alle ore 07:35:24