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Titolo:
[C-11] ACETATE AND [C-11] ]METHIONINE - IMPROVED SYNTHESES AND QUALITY-CONTROL
Autore:
BERRIDGE MS; CASSIDY EH; MIRALDI F;
Indirizzi:
CASE WESTERN RESERVE UNIV,DEPT RADIOL CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DEPT CHEM CLEVELAND OH 44106 UNIV CLEVELAND HOSP CLEVELAND OH 44106
Titolo Testata:
Applied radiation and isotopes
fascicolo: 3, volume: 46, anno: 1995,
pagine: 173 - 175
SICI:
0969-8043(1995)46:3<173:[AA[]->2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
M.S. Berridge et al., "[C-11] ACETATE AND [C-11] ]METHIONINE - IMPROVED SYNTHESES AND QUALITY-CONTROL", Applied radiation and isotopes, 46(3), 1995, pp. 173-175

Abstract

Two C-11-labeled radiopharmaceuticals which are routinely used in clinical PET procedures are [C-11]acetate and [C-11]methionine. In implementing published procedures for their synthesis, modifications of the procedures and chemistry were made to create a more rapid and reproducible production process for routine clinical application. We report simplified methods which allow a single apparatus to be used for all C-11 syntheses which use methyl iodide, Grignard reagents, or acetone as labeled synthetic precursors. A reliable TLC quality control method for [C-11]acetate is also reported.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 15:26:44