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Titolo:
ESTROGENS REDUCE PLASMA HISTIDINE-RICH GLYCOPROTEIN (HRG) LEVELS IN ADOSE-DEPENDENT WAY
Autore:
HENNIS BC; BOOMSMA DI; FIJNVANDRAAT K; LEUVEN JAG; PETERS M; KLUFT C;
Indirizzi:
TNO,PG,GAUBIUS LAB,POB 2215 2301 CE LEIDEN NETHERLANDS FREE UNIV AMSTERDAM,DEPT PSYCHONOM AMSTERDAM NETHERLANDS UNIV AMSTERDAM,EKZ CHILDRENS,ACAD MED CTR 1105 AZ AMSTERDAM NETHERLANDS
Titolo Testata:
Thrombosis and haemostasis
fascicolo: 3, volume: 73, anno: 1995,
pagine: 484 - 487
SICI:
0340-6245(1995)73:3<484:ERPHG(>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORAL-CONTRACEPTIVES; TALL STATURE; PLASMINOGEN; FIBRINOLYSIS; COAGULATION; AFFINITY; PROTEIN; SITES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
B.C. Hennis et al., "ESTROGENS REDUCE PLASMA HISTIDINE-RICH GLYCOPROTEIN (HRG) LEVELS IN ADOSE-DEPENDENT WAY", Thrombosis and haemostasis, 73(3), 1995, pp. 484-487

Abstract

Plasma levels of histidine-rich glycoprotein (HRG) were investigated in three groups of women receiving a different dose of estrogens. First, the effect of low-dose estrogen was studied in a group of 83 post menopausal women who were treated with 0.625 mg conjugated estrogens (CE). No significant change from baseline levels was found at the end ofcycle 3 and cycle 13. Secondly, in 15 mothers and 23 daughters using oral contraceptives (OC) containing 30-50 mu g ethinyl estradiol (EE) daily the mean HRG level was 14% and 24% lower than in a group of 144 mothers and 134 daughters not taking oral contraceptives. respectively(p < 0.05). Finally, in 11 excessively tall prepuberal girls who received 300 mu g EE daily to reduce their final height the mean plasma HRG levels were decreased by 68% (p < 0.005). The effect of progestogensadministered during low-dose and high-dose estrogen therapy appeared to be minor. The results from these three studies indicate that estrogens reduce plasma HRG levels in a dose-dependent way.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:28:42