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Titolo:
DELETION-6Q IN 3 CASES OF MIXED-TYPE LIPOSARCOMA IN ADDITION TO T(12-16)(Q13-P11)
Autore:
ALTUNGOZ O; MELONI AM; PEIER A; ZALUPSKI M; SPANIER S; BROOKS JSJ; SANDBERG AA;
Indirizzi:
SW BIOMED RES INST & GENETRIX INC,CTR CANC,6401 E THOMAS RD SCOTTSDALE AZ 85251 SW BIOMED RES INST & GENETRIX INC,CTR CANC SCOTTSDALE AZ 85251 WAYNE STATE UNIV,HARPER HOSP,SCH MED,DIV HEMATOL ONCOL DETROIT MI 48201 UNIV FLORIDA,COLL MED,DEPT ORTHOPED GAINESVILLE FL 00000 ROSWELL PK CANC INST BUFFALO NY 00000
Titolo Testata:
Cancer genetics and cytogenetics
fascicolo: 2, volume: 79, anno: 1995,
pagine: 104 - 110
SICI:
0165-4608(1995)79:2<104:DI3COM>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SOFT-TISSUE SARCOMAS; HUMAN-MALIGNANT MELANOMA; MYXOID LIPOSARCOMA; CYTOGENETIC ANALYSIS; TRANSLOCATION T(12-16)(Q13-P11); CHROMOSOME-ABNORMALITIES; CELL-LINES; TUMORS; HETEROZYGOSITY; LOCALIZATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
O. Altungoz et al., "DELETION-6Q IN 3 CASES OF MIXED-TYPE LIPOSARCOMA IN ADDITION TO T(12-16)(Q13-P11)", Cancer genetics and cytogenetics, 79(2), 1995, pp. 104-110

Abstract

We report the cytogenetic findings in three mixed liposarcoma following short-term cultures. During the course of cytogenetic investigationof various types of liposarcomas, we observed an interstitial deletion of the long arm of chromosome 6 together with the translocation (12;16) (q13;p11) in three tumors. Translocation (12;16) is associated with myxoid and mixed (myxoid/round cell) liposarcomas, although deletionof chromosome 6 has been observed in only a few of these tumors. Our findings suggest that del(6), as an additional change in myxoid liposarcoma, is probably related to tumor progression.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 21:09:07