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Titolo:
MR OF CEREBRAL ASPERGILLOSIS IN PATIENTS WHO HAVE HAD BONE-MARROW TRANSPLANTATION
Autore:
MIAUX Y; RIBAUD P; WILLIAMS M; GUERMAZI A; GLUCKMAN E; BROCHERIOU C; LAVALJEANTET M;
Indirizzi:
117 BLVD RICHARD LENOIR F-75011 PARIS FRANCE HOP ST LOUIS,DEPT RADIOL PARIS FRANCE HOP ST LOUIS,DEPT HEMATOL PARIS FRANCE HOP ST LOUIS,DEPT PATHOL PARIS FRANCE
Titolo Testata:
American journal of neuroradiology
fascicolo: 3, volume: 16, anno: 1995,
pagine: 555 - 562
SICI:
0195-6108(1995)16:3<555:MOCAIP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL NERVOUS-SYSTEM; IMMUNOSUPPRESSED PATIENTS; COMPUTED-TOMOGRAPHY; INFECTIONS; INFARCTION; CNS; ABSCESSES; CT;
Keywords:
ASPERGILLOSIS; BONE MARROW TRANSPLANTATION; BRAIN, MAGNETIC RESONANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
Y. Miaux et al., "MR OF CEREBRAL ASPERGILLOSIS IN PATIENTS WHO HAVE HAD BONE-MARROW TRANSPLANTATION", American journal of neuroradiology, 16(3), 1995, pp. 555-562

Abstract

PURPOSE: To assess the CT and MR appearance of cerebral aspergillosisin patients who have undergone bone marrow transplantation. METHODS: The imaging and clinical data of five patients with cerebral aspergillosis were reviewed retrospectively and compared with autopsy findings. RESULTS: Lesions are often located in the basal ganglia and demonstrate an intermediate signal intensity within surrounding high-signal areas on long-repetition-time MR scans. The lesions were multiple in fourof the five patients and more numerous on MR images than on CT scans. The lesions (which demonstrate no parenchymal enhancement) are consistent with acute infarcts as confirmed at autopsy. In the large lesions, there is early intravascular and meningeal enhancement, as expected in acute infarcts involving an appreciable portion of the territory ofa cerebral artery. CONCLUSION: The diagnosis of early cerebral infarction in a patient considered at risk for invasive aspergillosis, even without overt pulmonary disease, is an indication to institute aggressive antifungal therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 17:35:53